نتایج جستجو برای: HBV immune epitopes
تعداد نتایج: 297142 فیلتر نتایج به سال:
abstract background: naturally occurred hepatitis b virus (hbv) with surface mutations in a variety of chronic hepatitis b (chb) patients who have received no vaccine or hbig bearing substitutions in surface protein, have been reported. objectives: current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among iranian carriers is limited. patients and m...
background: hepatitis b virus (hbv) gene and protein variations are frequently been seen in chronic patients. the aims of study were to determine the genotypes as well as the patterns of variations distribution in chronically-infected patients from the central part of iran. methods: the surface gene was amplified, sequenced and subsequently aligned using international and national iranian datab...
objective(s) the aim of this study was to characterize the hepatitis b virus surface protein genotypes and sequence variations among hepatitis b virus surface antigen (hbsag) positive chronic patients in hormozgan province, south of iran. materials and methods a total of 8 patients enrolled in this study. the surface gene was amplified and directly sequenced. genotypes and nucleotide/amino acid...
Abstract Background: Naturally occurred hepatitis B virus (HBV) with surface mutations in a variety of chronic hepatitis B (CHB) patients who have received no vaccine or HBIG bearing substitutions in surface protein, have been reported. Objectives: Current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among Iranian carriers is limited. Patients and M...
Objective (s):The aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis B surface antigen (HBsAg)-positive chronic hepatitis B virus (HBV) patients. Materials and Methods: 16 patients received the HBV vaccine and another 16 individuals from the control group did not. The surface gene was amplified and directly sequenced from samples...
mutations in the human hepatitis b virus (hbv) genome contribute to its escape from host immune surveillance and result in persistent infections. the aim of this study was to characterize the molecular variations of the surface gene and protein in chronically-infected patients from the southern part of iran. the surface genes from 12 hbv chronic carriers were amplified, sequenced and ...
objective (s):the aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis b surface antigen (hbsag)-positive chronic hepatitis b virus (hbv) patients. materials and methods: 16 patients received the hbv vaccine and another 16 individuals from the control group did not. the surface gene was amplified and directly sequenced from samples ...
background co-infection with human immunodeficiency virus (hiv) and hepatitis b virus (hbv) is common due to shared routes of transmission, as reported approximately 10% of 33 million hiv-infected patients worldwide are chronically infected with hbv. mutations of hbsag especially within the “a” determinant could alter the antigenicity of the protein, causing failure of hbsag neutralization and ...
BACKGROUND Hepatitis B virus (HBV) gene and protein variations have frequently been observed in chronic patients. The aims of this study were to determine the genotypes as well as the patterns of HBsAg variations in chronically-infected patients from the south-eastern part of Iran. METHODS Twenty- one chronic inactive HBV carriers from Sistan-Balouchestan Province (an area with a low prevalen...
Hepatitis B virus (HBV) infection has persisted as a major public health problem due to the lack of an effective treatment for those chronically infected. Therapeutic vaccination holds promise, and targeting HBV polymerase is pivotal for viral eradication. In this research, a computational approach was employed to predict suitable HBV polymerase targeting multi-peptides for vaccine candidate se...
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