background: hepatitis b virus (hbv) gene and protein variations are frequently been seen in chronic patients. the aims of study were to determine the genotypes as well as the patterns of variations distribution in chronically-infected patients from the central part of iran. methods: the surface gene was amplified, sequenced and subsequently aligned using international and national iranian datab...

objective(s) the aim of this study was to characterize the hepatitis b virus surface protein genotypes and sequence variations among hepatitis b virus surface antigen (hbsag) positive chronic patients in hormozgan province, south of iran. materials and methods a total of 8 patients enrolled in this study. the surface gene was amplified and directly sequenced. genotypes and nucleotide/amino acid...

abstract background: naturally occurred hepatitis b virus (hbv) with surface mutations in a variety of chronic hepatitis b (chb) patients who have received no vaccine or hbig bearing substitutions in surface protein, have been reported. objectives: current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among iranian carriers is limited. patients and m...

background and aims: the aim of this study was to determine the correlation between the hepatitis b virus surface ag (hbsag) genotypes and variations in the clinical/serological pictures among hbsag positive chronic patients from south khorasan province of iran. methods: twenty-five patients were enrolled in this study. the hbs ag gene was amplified and was directly sequenced. genotypes and nuc...

conclusions genotype d was the main genotype detected in romanian patients with chronic hbv infection. genotype d presented both bcp and pc mutations more frequently. results we detected two hbv genotypes; a (8.1%) and d (60.5%), and a mixture of genotypes a and d (31.4%) (p < 0.001). basal core promoter (bcp) a1762t/g1764a and precore (pc) g1896a mutations were detected in these romanian patie...

Background and Aims: Hepatitis B virus (HBV) infects the liver and causes acute and chronic hepatitis, hepatocellular carcinoma and cirrhosis. HBV has been divided to eight genotypes (A–H) and subgenotypes of A, B, C and F. For the first time, we determined HBV genotypes in infected samples by INNO-LiPA method in Yazd, central province of Iran. Materials and Methods: This study was performed...

    Background: Hepatitis B Virus (HBV) causes acute and chronic liver disease worldwide. HBV has eight genotypes (A to H) which is the reflection of its genome with their characteristic geographical distribution. Each genotype could have different pathogenic and therapeutic characteristics. There have been few records on HBV genotyping in general population from our region. This study aimed to...

AIM To study the Hepatitis B virus (HBV) genotypes and their effect on the progression and outcome in patients with chronic liver diseases from New Delhi, India. METHODS Sera from 100 HBV-related chronic liver disease (CLDB) cases were tested for HBV genotype using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) and Type-specific primers-based PCR (TSP-PCR) targe...

conclusions the present clinical study suggests that the transmission of an hbv genotype other than genotype d, namely hbv genotype g, is possible in turkey. epidemiological and clinical information on genotype g infection is currently limited, and this is most likely due to its low prevalence throughout the world. therefore, it may be important to determine the epidemiologic and molecular char...