conclusions a(h1n1)pdm09 viruses, identified in this study in shiraz, iran, contained 5 site specific mutations and were susceptible to oseltamivir. results our results revealed that a(h1n1)pdm09 viruses present in these samples were susceptible to oseltamivir, and contained 5 site specific mutations (v13g, v106i, v241i, n248d, and n369k) in na gene. these mutations correlated with increasing e...

Background: World Health Organization declared pandemic phase of human infection with novel influenza A (H1N1) in April 2009. There are very few reports about the neurological complications of H1N1 virus infection in the literature. Occasionally, these complications are severe and even fatal in some individuals. The aims of this study were to report neurological complaints and/or complications ...

Subtype H1N1 influenza A virus (IAV) that caused a pandemic in 2009, called A(H1N1)pdm09, has been circulating as seasonal IAV among humans, escaping from herd immunity through amino acid substitutions hemagglutinin (HA). Additionally, position 162 of HA A(H1N1)pdm09 evolved to be N-linked glycosylated by 2017. Here the effect glycosylation at was examined comparing ratio nonsynonymous diversit...

Background: A new pandemic influenza A (H1N1) emerged in April 2009, causing considerable morbidity and mortality. Since mutations in the haemagglutinin (HA) may influence the antigenicity and pathogenicity of the virus, continued epidemiological and molecular characterization for the effective control of pandemic flu and developing of more appropriate vaccine is crucial. Objective: To monitor ...

background: world health organization declared pandemic phase of human infection with novel influenza a (h1n1) in april 2009. there are very few reports about the neurological complications of h1n1 virus infection in the literature. occasionally, these complications are severe and even fatal in some individuals. the aims of this study were to report neurological complaints and/or complications ...