granulomatous response in association with breast cancer and within the cancer draining lymph nodes is an extremely rare phenomenon. granulomatous inflammation is an immune response commonly seen against infectious agents and certain non-neoplastic conditions. the etiopathogenesis of granulomas associated with malignancies is not clear but it may be because of an immunologic reaction to tumour ...

Granulomatous response in association with breast cancer and within the cancer draining lymph nodes is an extremely rare phenomenon. Granulomatous inflammation is an immune response commonly seen against infectious agents and certain non-neoplastic conditions. The etiopathogenesis of granulomas associated with malignancies is not clear but it may be because of an immunologic reaction to tumour ...

chronic granulomatous disease is an inherited defect in intracellular killing of ingested microorganisms characterized by recurrent life threatening bacterial and fungal infections including invasive aspergillosis in early childhood. we report  a  disseminated aspergillosis as  the  representative  of  adult  onset  chronic granulomatous disease without previous infection, with dramatic respons...

bcg (bacille calmette–guérin) vaccine is administered worldwide to prevent severe forms of tuberculosis. it is considered to be safe; however, occasional complications are seen. the most serious complication is bcgosis. we report a case of bcgosis with granulomatous hepatitis and acid-fast bacilli in liver and spleen. we treated the patient with antituberculosis drugs without any response to tr...

Cord factor in the form of emulsion is unable to sensitize mice to react with a more extensive granulomatous response to a subsequent challenge with the same substance. Mice infected with BCG bacilli are sensitized to cord factor. Such animals react to administration of cord factor with a very extensive granulomatous response, much stronger than normal ones. This hypersensitivity seems to be sp...

Granulomatous inflammation in the lung may occur from a variety of causes. Many of these are the result of specific antigens that reach the lung and induce a granulomatous response. A prototype of this schema is pulmonary tuberculosis where the organism serves as the inciting antigen. Treatment of tuberculosis is aimed at killing and clearing the organism. It would be foolhardy and potentially ...

Intracranial germinomas are rare and account for <0.5% of primary intracranial tumors. In contrast to the gonadal germinomas, these do not show granulomatous response within the tumor. In rare cases, the granulomatous component may obscure the tumor proper and lead to diagnostic difficulties/dilemmas. We report a case of suprasellar germinoma in a 17-year-old boy which showed granulomatous resp...

The granulomatous inflammatory response is a special type of chronic inflammation characterised by often focal collections of macrophages, epithelioid cells and multinucleated giant cells. In this review the characteristics of these cells of the mononuclear phagocyte series are considered, with particular reference to the properties of epithelioid cells and the formation of multinucleated giant...