The citrate reduction method for the synthesis of gold nanoparticles (GNPs) has known advantages but usually provides the products with low nanoparticle concentration and limits its application. Herein, we report a facile method to synthesize GNPs from concentrated chloroauric acid (2.5 mM) via adding sodium hydroxide and controlling the temperature. It was found that adding a proper amount of ...

Detecting is the most important section in all kinds of sensors. In this regard, the amplification of surface plasmon resonance intensity of gold colloids nanoparticles (GNPs) was studied in the presence of several ions. GNPs were synthesized and then capped by thiocyanate and characterized via DLS and TEM image. In the next step the effect of different concentrations of ions such as iron, copp...

Detecting is the most important section in all kinds of sensors. In this regard, the amplification of surface plasmon resonance intensity of gold colloids nanoparticles (GNPs) was studied in the presence of several ions. GNPs were synthesized and then capped by thiocyanate and characterized via DLS and TEM image. In the next step the effect of different concentrations of ions such as iron, copp...

PURPOSE Nanotechnology is an emerging field with significant translational potential in medicine. In this study, we applied gold nanoparticles (GNP) to enhance radiation sensitivity and growth inhibition in radiation-resistant human prostate cancer cells. METHODS Gold nanoparticles (GNPs) were synthesized using HAuCl4 as the gold particle source and NaBH4 as the reductant. Either thio-glucose...

Bactericidal efficacy of gold nanoparticles conjugated with ampicillin, streptomycin and kanamycin were evaluated. Gold nanoparticles (Gnps) were conjugated with the antibiotics during the synthesis of nanoparticles utilizing the combined reducing property of antibiotics and sodium borohydride. The conjugation of nanoparticles was confirmed by dynamic light scattering (DLS) and electron microsc...

one of the applications of gold nanoparticles (gnps) in medicine is radiation dose-enhancing effect. although there are many simulations, in vitro and in vivo evidence that gnps can enhance significantly the radiation dose effect of orthovoltage beams. these beams compared with megavoltage (mv) beams, have limited applications in radiotherapy. in order to evaluate gnps radiosensitization perfor...

conclusions due to the significant reduction in the mean inactivation dose of colon cancer cells in the presence of gold nanoparticles, it seems that gnps are suitable options to achieve a new approach in order to improve radiotherapy efficiency without increasing the prescribed radiation dose. results cell survival in the presence of gnps was more than 90% and the maximum uptake of gnps was ob...

objective(s): biological applications of gold nanoparticles have limitations because of the toxic chemicals used in their synthesis. curcumin can be used as reducing as well as capping agent in synthesis of gnps to eliminate the cytotoxicity. conjugation of curcumin to gold also helps in increasing its solubility and bioavailability. materials and methods: here we report synthesis of gold nanop...

The synthesis and biomedical application of noble metal nanoparticles specially gold nanoparticles (GNPs) is a promising field of research and has garnered the attention of vast groups of researchers. Bulk metallic gold (Au) is known to be chemically inert. However, when the size of gold is reduced to nanometer ranges it starts to show diverse biological properties [1]. GNPs find application in...

Nowadays, modified electrodes with metal nanoparticles have appeared as an alternative for the electroanalysis of various compounds. In this study, gold nanoparticles (GNPs) were chosen as interesting metal nanoparticles for modifying of carbon paste electrode (CPE). GNPs and the gold nanoparticles-modified carbon paste electrode (GNPs/CPE) were characterized by UV-Vis spectroscopy, transmissio...