introduction: the aim of this study was to demonstrate changes in nature of mucin and production of acidic forms using pas-alcian blue stain at ph=2.5. appearance of non-goblet metaplastic columnar cells of lower esophagus is considered as an early sign of barrette sophagus, simultaneous in conjunction or before the appearance of goblet cells in patients with gastroesophageal reflux disease. ma...

Background: IBD is a chronic inflammatory condition associated with damage to the intestinal mucosal barrier. Supplementation of yacon tubers has been known to give positive effect in intestinal health. Therefore, we conducted the study to investigate the effect of yacon tuber powder on Th1 activation pathway by evaluating IFN-γ levels and the number of goblet cells in the colon of colitis mous...

The aim of the current study was to investigate the histological and histochemical characteristics of large and small intestines of sea snake, Hydrophis cyanocinctus. Six adult sea snakes were collected from Minab beaches, located near the sea of Oman, in November, euthanized with chloroform, dissected and alimentary canal removed, tissues preparaed for sectioning and staining with Hematoxylin ...

Background and Objectives: Primary acquired nasolacrimal duct obstruction (PANDO) is a common ocular problem. Clinical presentation can range from simple tearing to a life-threatening condition. The exact pathophysiology of obstruction is not completely understood. In this study, therelationship between PANDO and nasal mucosal goblet cells was investigated.  Materials & Methods: In this case-c...

OASIS is a basic leucine zipper transmembrane transcription factor localized in the endoplasmic reticulum (ER) that is cleaved in its transmembrane region in response to ER stress. This novel ER stress transducer has been demonstrated to express in osteoblasts and astrocytes and promote terminal maturation of these cells. Additionally, OASIS is highly expressed in goblet cells of the large inte...

Cancer can significantly have ruining effects on very high of human beings, social, and economic condition. Bladder cancer has been reported as one of the most common cancers and the incidence rates of this cancer is increasing across the world. Cystectomy is a surgery to remove the urinary bladder. In the present study a part of the ileum is used instead of bladder. This study deals with mucos...

PURPOSE To isolate and characterize goblet cells from normal human conjunctival tissue to determine whether epidermal growth factor (EGF) receptors are present and whether EGF can influence goblet cell proliferation. METHODS Goblet cells were isolated from explant cultures established from normal conjunctival tissue harvested from patients during periocular surgery. The cells were grown in RP...

background: from the time immemorial man has been exposed to ionizing radiation from the environment in which he lives. radiation protection concepts and philosophy have been evolving over the past several decades. materials and methods: the radioprotective of effect of aloe vera leaf extract (1000 mg /kg b.wt. orally for 15 consecutive days) has been studied against 6 gy of gamma radiation in ...

Halm, Dan R., and Susan Troutman Halm. Secretagogue response of goblet cells and columnar cells in human colonic crypts. Am. J. Physiol. Cell Physiol. 278: C212–C233, 2000.—Crypts of Lieberkühn were isolated from human colon, and differential interference contrast microscopy distinguished goblet and columnar cells. Activation with carbachol (CCh, 100 μM) or histamine (10 μM) released contents f...

Various acute and chronic inflammatory stimuli increase the number and activity of pulmonary mucus-producing goblet cells, and goblet cell hyperplasia and excess mucus production are central to the pathogenesis of chronic pulmonary diseases. However, little is known about the transcriptional programs that regulate goblet cell differentiation. Here, we show that SAM-pointed domain-containing Ets...