conclusions it can be concluded that the nettle extract can reduce blood glucose levels in diabetic mice, at least partly, by influencing the glut2 gene expression in mice liver. results the results showed that the nettle extract significantly decreased high levels of blood glucose (p < 0.001). the nettle extract also had a preventive effect on decrease in body weight. in addition, the results ...

Glucose is an osmotic agent in the peritoneal dialysis fluid (PDF) to absorb water, sodium and other toxins. absorption from PDF blood impairs (PD) efficiency cause glycemic burden. This extra load leads poor control diabetic patients with PD program. Studies have shown sodium-glucose co-transporter (SGLT)-2 expression mesothelial cells. Blockade of SGLT reduced glucose increment increased rete...

To clarify the function of the Na(+)-coupled glucose transporter in the regulation of cellular tone of cultured retinal pericytes, we investigated the effects of extracellular glucose concentration on cell size. The surface area and diameter of cultured bovine retinal pericytes under different glucose concentrations were measured by using a light microscope with a digital camera. We also examin...

Complementary DNA encoding a facilitative glucose transporter was isolated from a human hepatoma cell line (HepG2) cDNA library and subcloned into a metal-inducible mammalian expression vector, pLEN (California Biotechnology) containing human metallothionein gene II promoter sequences. Chinese hamster ovary (CHO) cells transfected with this transporter expression vector, pLENGT, exhibited a 2-1...

Nephrolithiasis is one of the common diseases without effective treatment, incidence which has increased in world recent decades. Sodium-glucose co-transporter 2 inhibitor can reduce probability nephrolithiasis diabetic and non-diabetic people.

Diabetes Mellitus (DM) is an incurable disease that can be prevented clinically from worsening. This based on classification related to pancreatic damage in total or partial so the impact insulin production. Glucose transporter a protein glucose uptake outside cell into and provides important role body's homeostasis. transporter-2 (GLUT-2) found pancreas, liver, kidney. Parameters used are expr...

Sodium-glucose co-transporter 2 (SGLT2) inhibitors may decrease risk of renal function deterioration and proteinuria progression but, there are little clinical data about the comparison between dapagliflozin (DAPA) versus empagliflozin (EMPA) in patients with diabetes mellitus (DM) over one year time. Inhere,we directly compare effectiveness two distinct sodium-glucose co-transporter2 (SGLT2I) ...

We describe an implemented model of glucose absorption in the enterocyte, as previously published by Afshar et al. (2019), The used mechanistic descriptions all responsible transporters and was built CellML framework. It validated against experimental data a modular structure which allows each individual transporter to be edited independently from other transport protein models. composite then ...