نتایج جستجو برای: Giant Cell Glioblastomas

تعداد نتایج: 1728482  

Journal: :iranian journal of pathology 2011
indranil chakrabarti nilanjana ghosh

giant cell glioblastoma is an extremely rare variant of glioblastoma (who grade iv) which is characterized by a predominance of bizarre, multinucleated giant cells. these tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. in pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. here, we report a case of a 12-year old female pati...

Indranil Chakrabarti, Nilanjana Ghosh

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

2012
Franz-Josef Klinz Sergej Telentschak Roland Goldbrunner Klaus Addicks

Glioblastoma multiforme (GBM; WHO grade IV) is the most malignant type of glioma and in addition the most abundant malignant cancer of the adult human brain. Despite progress in diagnosis, surgery and chemotherapy, the median survival time of patients suffering from GBM is approximately 15 months (Stupp et al., 2005). The five years survival time is less than 5% (CBTRUS, 2010). Because glioblas...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013
W Caleb Rutledge Jun Kong Jingjing Gao David A Gutman Lee A D Cooper Christina Appin Yuna Park Lisa Scarpace Tom Mikkelsen Mark L Cohen Kenneth D Aldape Roger E McLendon Norman L Lehman C Ryan Miller Matthew J Schniederjan Cameron W Brennan Joel H Saltz Carlos S Moreno Daniel J Brat

PURPOSE Tumor-infiltrating lymphocytes (TIL) have prognostic significance in many cancers, yet their roles in glioblastoma have not been fully defined. We hypothesized that TILs in glioblastoma are associated with molecular alterations, histologies, and survival. EXPERIMENTAL DESIGN We used data from The Cancer Genome Atlas (TCGA) to investigate molecular, histologic, and clinical correlates ...

2013
David A. Gutman Lee A.D. Cooper Christina Appin Yuna Park Lisa Scarpace Tom Mikkelsen Mark L. Cohen Kenneth D. Aldape Roger E. McLendon Norman L. Lehman C. Ryan Miller Matthew J. Schniederjan Cameron W. Brennan Joel H. Saltz Daniel J. Brat

Purpose: Tumor-infiltrating lymphocytes (TIL) have prognostic significance in many cancers, yet their roles in glioblastoma have not been fully defined. We hypothesized that TILs in glioblastoma are associated with molecular alterations, histologies, and survival. Experimental Design: We used data from The Cancer Genome Atlas (TCGA) to investigate molecular, histologic, and clinical correlates ...

Journal: :the archives of bone and joint surgery 0
anshul sobti department of orthopaedics, p.d hinduja national hospital and medical research centre, veer savarkar marg, mahim, mumbai, india pranshu agrawal department of orthopaedics, p.d hinduja national hospital and medical research centre, veer savarkar marg, mahim, mumbai, india sanjay agarwala head of surgey & orthopaedics, consultant in orthopaedics trauma & arthroplasty, p.d hinduja national hospital and medical research centre, veer savarkar marg mahim, mumbai, india manish agarwal consultant in orthopaedic oncology & soft tissue tumors, hinduja national hospital and medical research centre, veer savarkar marg mahim, mumbai, india

giant cell tumors (gct) are benign tumors with potential for aggressive behavior and capacity to metastasize. although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. its histogenesis remains unclear. it is characterized by a proliferation of mononuclear stromal ce...

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی استان کرمان 1376

بر اساس تجربیات انتقال دیستال اولنا یک روش خوب ترمیم بعد از اکسیزیون دیستال رادیوس بویژه در بیماران مبتلا به giant cell tumor می باشد. در این روش عود و عوارض بعد از عمل بسیار ناچیز بوده و حرکات دست در حد قابل قبولی برای بیمار حفظ می شود ولی قدرت عضلات از نوع grip دست عمل شده در حدود 75 - 50 درصد کاهش می یابد. مشکل بیمار بیشتر بعد از عمل می باشد زیرا به مدت 6 ماه باید دست داخل گچ باشد و مدت 6 ما...

2011
Indranil Chakrabarti Nilanjana Ghosh

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12year old female patie...

Journal: :Clinical neurosurgery 2005
Maria Salpietro Eric C Holland

Glioma is the most common form of primary brain tumor. Although surgical resection of the tumor may be achieved, recurrence is almost inevitable because of the propensity of gliomas for infiltrative growth far into functionally intact brain tissue. Gliomas are classified into four clinical grades, with glioblastoma multiforme (GBM) being the most aggressive type (World Health Organization [WHO]...

Journal: :Neuro-oncology 1999
P Kleihues H Ohgaki

Glioblastomas may develop de novo (primary glioblastomas) or through progression from low-grade or anaplastic astrocytomas, (secondary glioblastomas). These subtypes of glioblastoma constitute distinct disease entities that evolve through different genetic pathways, affect patients at different ages, and are likely to differ in prognosis and response to therapy. Primary glioblastomas develop in...

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