today, chronic viral hepatitis is considered as a public health problem in the world. totally, 5% of the world population, especially in asia and africa suffer from this problem. the prevalence of acute hepatitis in america is 0.1-0.2 percent, 50% of those with hepatitis c (hcv) and 5-10% of them with hepatitis b (hcv) develop chronic hepatitis. determining hbv and hcv genotypes is important to...

The distribution found by compounding the multinomial distribution with the Dirichlet distribution has been suggested as a basis for the estimation of parameters in subdivided populations, in particular of the "correlation between genotypes" within subpopulations. It is shown that the estimators deriving from these procedures perform poorly when the data are generated by the classical Wright dr...

conclusions our results showed that hcv genotype 4 is the most prevalent genotype in the middle east region. however, hcv genotype 1 is the most prevalent among non-arab countries in the region including turkey, iran, cyprus, and israel. context the hepatitis c virus (hcv) is classified into seven genotypes and more than 100 subtypes. the treatment regimen, duration and efficacy of hcv therapy ...

results of 1818 hcv rna positive samples, hcv genotypes pcr fragments were detected in 1552 (85.5%) samples. hcv genotype 3a was the predominant genotype (39.4%) followed by genotype 2a (24.93%). hcv genotype 3 was the predominant genotype in punjab and sindh regions, while genotype 2 was the most predominant genotype in khyber pakhtunkhwa region and the second predominant genotype after genoty...

  Purpose: Estrogen as a crucial hormone during pregnancy acts by two types of receptors.   Estrogen receptor alpha, expressed by estrogen receptor 1 (ESR1) gene, is more abundant and   exists in all human reproductive systems. Association of ESR1 gene polymorphism has been   shown in some reproductive fields such as spontaneous abortion, endometriosis-related infertility   and in vitro fertili...

background il28b polymorphism is recognized as one of the most prominent predictors of hepatitis c spontaneous and treatment-induced clearance. interestingly, the favorable genotypes of il28b are found to be more frequent in asian ethnicity than caucasian and african populations, respectively. a few studies reported that there is a mysterious association between the il28b polymorphism and the h...