background: ingestion of caustic substances is the main reason for referral to philippines national poison management and control center among other causes of acute poisoning. rapid assessment of severity of injury is important for treatment and prognosis of these cases. this study was aimed to investigate the correlation of clinical factors with severity of gastrointestinal (gi) mucosal injury...

Approximately 20% of caustic ingestions result in some degree of esophageal injury. Alkaline materials are the most frequent corrosive materials ingested.     The physical form and PH of ingested materials play a critical role in the site and type of gastrointestinal injury (PH > 12 or PH < 1.5, crystalline drain cleaners). Unlike Alkaline solutions, strong acids are bitter, burn on contact and...

conclusions all of the gynecologic surgeons must be aware of gastrointestinal injuries and should anticipate injury to these organs especially in high-risk patients for decreasing patient morbidity. results the mean age of women was 33.2 ± 7.57 years. 44% of the patients had a history of abdominal scar. 32% of all gi injuries occurred during total abdominal hysterectomy (tah). the small bowel w...

Antithrombotic drugs have been increasingly used for treating ischemic cardiovascular diseases among the elderly in Japan. However, antithrombotic drugs are known to be risk factors for gastrointestinal injury. Therefore, we conducted a pharmacoepidemiologic study on patients receiving antithrombotic drugs to identify the risk factors for gastrointestinal injury. This retrospective case-control...

Gastrointestinal ischemia-reperfusion (I/R) injury is often associated with remote tissue injury. Complement activation plays an important role in local and remote tissue injury associated with gastrointestinal I/R. We developed a new murine model of gastrointestinal I/R that has complement-dependent local and remote tissue injury. Twenty, but not thirty, minutes of gastrointestinal ischemia fo...

approximately 20% of caustic ingestions result in some degree of esophageal injury. alkaline materials are the most frequent corrosive materials ingested.     the physical form and ph of ingested materials play a critical role in the site and type of gastrointestinal injury (ph > 12 or ph < 1.5, crystalline drain cleaners). unlike alkaline solutions, strong acids are bitter, burn on contact and...

BACKGROUND This study aimed to determine the potential protective effect of inducing hypertransfusion to the gastrointestinal tract following a porcine model of cardiac arrest and cardiopulmonary resuscitation (CPR) by evaluating the influence of gastrointestinal ultrastructure, ATPase and serum diamine oxidase. METHODS Ventricular fibrillation was induced by programmed electrical stimulation...

As a complication in patients with head injury or cerebral stroke, gastrointestinal bleeding is an important problem in neurosurgery. We reviewed 411 cases of hypertensive intracerebral hemorrhage, ruptured cerebral aneurysm and severe head injury in order to ascertain the pathologic condition of the gastrointestinal bleeding and to introduce an effective method of therapy. In 411 cases, gastro...