نتایج جستجو برای: Gastro-Entero-Pancreatic (GEP)
تعداد نتایج: 94792 فیلتر نتایج به سال:
OWING to the association between alcohol and chronic pancreatitis in man' there has,been considerable interest in the effect of alcohol upon gastro-entero pancreatic (GEP) hormones. Previous estimations of GEP hormones following oral alcohol ingestion have shown raised serum gastrin concentrations in response to 18 per cent and 15 per cent ethanol in man (Becker, Reeder and Thompson2), and Stra...
OBJECTIVES To investigate whether screening for malnutrition using the validated malnutrition universal screening tool (MUST) identifies specific characteristics of patients at risk, in patients with gastro-entero-pancreatic neuroendocrine tumours (GEP-NET). DESIGN Cross-sectional study. SETTING University Hospitals Coventry & Warwickshire NHS Trust; European Neuroendocrine Tumour Society C...
Neuroendocrine tumors, or more properly gastro-entero-pancreatic tumors (GEP-NETs), are cancers of the interface between the endocrine (hormonal) system and the nervous system. A neuroendocrine tumor begins in the hormone-producing cells of the body’s neuroendocrine system, which is made up of cells that are a cross between traditional endocrine cells (or hormone-producing cells) and nerve cell...
A meta-analysis has systematically investigated the antineoplastic efficacy and safety of somatostatin analogs (SSAs) in advanced gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs). Randomized controlled trials (RCTs) reporting the hazard ratio (HR) for disease progression (DP) were evaluated. Response rate and risk ratio (RR) for adverse events were also analyzed. A total of 289 patient...
An increased interest in gastro-entero-pancreatic neuroendocrine neoplasms (GEP NENs) has recently been observed. These are rare neoplasms and their detection in recent years has improved. Over 50% of GEP NENs are carcinoids, and they are usually found incidentally during surgery in the small intestine and appendix and at diagnosis in distant metastases, mainly to the liver. There is a need for...
BACKGROUND Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) are relatively rare tumors, not equally distributed in the gastrointestinal system. In 2010, a revised version of the WHO classification of GEP-NENs was published. This study reports for the first time the distribution and characteristics of GEP-NENs in a Lebanese population. MATERIALS AND METHODS This descriptive retrospe...
Gastro-Entero-Pancreatic (GEP) NETs originate from both pancreatic islet cells or gastroenteric tissue (from diffuse neuroendocrine cells distributed throughout the gut) and are rare neoplasms, representing about 2% of all the gastrointestinal tumors. Due to their rarity, they are difficult to diagnose and the begnning of the diagnostic process is often based on the measurement of circulating m...
Background The glyoxalase-1 gene (GLO1) is a hotspot for copy-number variation (CNV) in human genomes. Increased GLO1 copy-number is associated with multidrug resistance in tumour chemotherapy, but prevalence of GLO1 CNV in gastro-entero-pancreatic neuroendocrine tumours (GEP-NET) is unknown. Methods GLO1 copy-number variation was measured in 39 patients with GEP-NET (midgut NET, n = 25; panc...
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