Interior topological features, such as pockets and channels, have evolved in proteins to regulate biological functions by facilitating the diffusion of biomolecules. Decades of research using the globins as model heme proteins have clearly highlighted the importance of gas pockets around the heme in controlling the capture and release of O(2). However, much less is known about how ligand migrat...

While the average metallicity of the intergalactic medium rises above Z & 10Z⊙ by the end of the reionization, pockets of metal-free gas can still exist at later times. We quantify the presence of a long tail in the formation rate of metalfree halos during late stages of reionization (redshift z ≈ 6), which might offer the best window to detect Population III stars. Using cosmological simulatio...

In the Netherlands, wastewater is collected in municipal areas and transported to centralised WWTPs by an extensive system of pressure mains. Over the last decades these pressure mains did not receive much attention in terms of monitoring of performance or maintenance. A recent inventory showed that half of the pressure mains show an increased pressure loss for no directly obvious reason. One o...

Electron microscopy of the cells of the thermogenic appendix of Sauromatum guttatum has revealed a fusion event between pocket-like structures of the rough endoplasmic reticulum (rER) and the plasma membrane. As a result of the fusion event, many regions of the plasma membrane have paired unit membranes (four leaflets instead of two). The fusion allows the transfer of osmiophilic material from ...

Entrapment of gas bubbles at the liquid/solid interface plays a crucial role for fluidic systems when the volume to surface ratio goes down. Here, we report an investigation on the presence of air on hydrophobic surfaces in water. The gas pockets on such walls are expanded, and thus made visible, by lowering the liquid pressure, a phenomenon known as heterogeneous cavitation. The investigation ...

This paper focuses on the notion of ‘pockets of effectiveness’ in the light of the theorisation of regulated neopatrimonialism. The attention to pockets of effectiveness – understood as public organisations which deliver public goods and services relatively effectively in contexts of largely ineffective government – adds to the understanding of regulated neopatrimonialism by focusing on the con...

INTRODUCTION Gas is rarely found within the viscera outside the lumen of the gastrointestinal tract. Emphysematous gastritis is a rare form of infection of the stomach wall by gas producing organisms. CLINICAL PICTURE A 45-year-old Chinese lady underwent hepatectomy for hepatocellular carcinoma. Postoperatively, she turned septic and encephalopathic with worsening liver function. Computed tom...