The biochemical diagnosis of 21-hydroxylase deficiency (21-OHD) is difficult in preterm infants. To date, no marker for the biochemical diagnosis of 21-OHD has been found. Seventeen α-hydroxyprogesterone (17-OHP), is not useful because of interference by delta 5 steroids from the fetal adrenal cortex. A 5-d-old female infant, born at 31 wk of gestation, was suspected of having 21-OHD based on p...

A novel, selective and sensitive single-ion monitoring (SIM) gas chromatography-mass spectrometry (GCMS) method was developed and validated for the determination of energy metabolites related to glycolysis, the tricarboxylic acid (TCA) cycle, glutaminolysis, and fatty acid β-oxidation. This assay used N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) containing 1% tert-butyldimethy...

Cloud water samples from Whiteface Mountain, NY were used to develop a combined sampling and gas chromatography-mass spectrometric (GCMS) protocol for evaluating the complex mixture of highly polar organic compounds (HPOC) present in this atmospheric medium. Specific HPOC of interest were mono- and di keto-acids which are thought to originate from photochemical reactions of volatile unsaturated...

BACKGROUND A gas chromatography mass spectrometry (GCMS) method for the determination of diclofenac in human plasma has been developed and validated. RESULTS This method utilizes hexane which is a relatively less toxic extraction solvent compared to heptane and benzene. In addition, phosphoric acid and acetone were added to the samples as deproteination agents, which increased the recovery of...

Abbreviations: L. barbarum, Lycium barbarum L.; LBP RAPD, Random Amplified Polymorphic DNA; FTIR, Four GCMS, gas-chromatographic–mass spectrometry; HRESI photo diode array detection–mass spectrometry; APC detection-mass spectrometry method with electrospray GlcAsA, 2-O-glucosyl-L-ascorbic acid; PSQI, Pittsburgh Sl endoplasmic reticulum; PERK, PKR-like ER kinase; NMD blood cells; MMC, mitomycin ...

This paper describes J-Sim v. 0.1.1, an object-oriented library using the method of pseudoparallel execution for simulation of discrete processes. Being written in Java, J-Sim is a fully portable successor to C-Sim, an already existing Cbased library. The concepts used in both libraries are inherited from the Simula language. In this paper, the theoretical background as well as the basic princi...

Extreme precipitation events over India have resulted in loss of human lives and damaged infrastructures, food crops, and lifelines. The inability of climate models to credibly project precipitation extremes in India has not been helpful to longer-term hazards resilience policy. However, there have been claims that finer-resolution and regional climate models may improve projections. The claims...

Let V and W be two real vector spaces and let &sim be a relation on both V and W. A linear function T : V → W is said to be a linear preserver (respectively strong linear preserver) of &sim if Tx &sim Ty whenever x &sim y (respectively Tx &sim Ty if and only if x &sim y). In this paper we characterize all linear functions T : M_{n,m} → M_{n,k} which preserve or strongly preserve multivariate an...

► SiM would in future publish three issues per year; ► SiM would only accept papers that deal with fungal cultures, and/or fungal DNA, which should be deposited at CBS to be optimally accessible to the scientific community; ► SiM would publish papers by invitation or if a volume or special topic was supported by one of its associate editors; ► SiM would move to a print-on-demand system that all...

Ecological niche models are widely used for mapping the distribution of species during the last glacial maximum (LGM). Although the selection of the variables and General Circulation Models (GCMs) used for constructing those maps determine the model predictions, we still lack a discussion about which variables and which GCM should be included in the analysis and why. Here, we analyzed the clima...