نتایج جستجو برای: Fusion protein vaccine

تعداد نتایج: 1413089  

Journal: :iranian journal of basic medical sciences 0
jafar amani applied microbiology research center, baqiyatallah university of medical sciences, tehran, iran amir ghasemi molecular biology research center, baqiyatallah university of medical sciences, tehran, iran reza ranjbar molecular biology research center, baqiyatallah university of medical sciences, tehran, iran mahdi shabani monoclonal antibody research center, avicenna research institute, acecr, tehran, iran mahdi zandemami monoclonal antibody research center, avicenna research institute, acecr, tehran, iran reza golmohammadi molecular biology research center, baqiyatallah university of medical sciences, tehran, iran

objective(s): brucella spp. are facultative intracellular pathogens which can stay alive and multiply in professional and nonprofessional phagocytes. immunity against brucella melitensis involves antigen-specific cd4+ and cd8+ t-cells activation and humoral immune responses. due to negative aspects of live attenuated vaccines, much attention has been focused on finding brucella-protective antig...

Journal: :iranian journal of basic medical sciences 0
jamshid faghri department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran delavar shahbazzadeh biotechnology research centre, pasteur institute of iran, tehran, iran kamran pooshang bagheri biotechnology research centre, pasteur institute of iran, tehran, iran sharareh moghim department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran hajieh ghasemian safaei department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran bahram nasr esfahani department of bacteriology and virology, faculty of medicine , isfahan university of medical sciences, isfahan, iran

objective(s) staphylococcus aureus is a foremost source of numerous nosocomial and community acquired infections. antibiotic therapy for vancomycin resistant s. aureus (vrsa) can not promise the eradication of infections. since adhesion is the major route of infections, adhesin based vaccine could suppress s. aureus infections. fibronectin binding protein a (fnbpa) and clumping factor a (clfa) ...

Journal: :iranian journal of basic medical sciences 0
jamshid faghri department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran kamran pooshang bagheri department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran delavar shahbaz zadeh department of biotechnology, pasteur institute of iran, tehran, iran rahmatolah yazdani department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran hamid mirmohammad sadeghi department of biotechnology, faculty of pharmacy, isfahan university of medical sciences, isfahan, iran sharareh moghim department of bacteriology and virology, faculty of medicine, isfahan university of medical sciences, isfahan, iran

objective(s) staphylococcus aureus is a leading cause of many nosocomial and community acquired infections. according to many reports, antibiotic therapy can not guarantee the eradication of s. aureus infections. thus designing an adhesin based vaccine could restrain the s. aureus infections. this study designed for construction of a new fusion protein vaccine against s. aureus infections based...

Bahram Nasr Esfahani Delavar Shahbazzadeh Hajieh Ghasemian Safaei Hamid Mirmohammad Sadeghi Hossein Fazeli, Jamshid Faghri, Kamran Pooshang Bagheri, Rahmatolah Yazdani Sharareh Moghim,

Objective(s) Staphylococcus aureus is a foremost source of numerous nosocomial and community acquired infections. Antibiotic therapy for vancomycin resistant S. aureus (VRSA) can not promise the eradication of infections. Since adhesion is the major route of infections, adhesin based vaccine could suppress S. aureus infections. Fibronectin binding protein A (FnBPA) and clumping factor A (ClfA)...

Asghar Tanomand, Jafar Majidi, Safar Farajnia, Shahin Najar,

Background: Infections due to Pseudomonas aeruginosa are among the leading causes of morbidity and mortality in patients who suffer from impaired immune responses and chronic diseases such as cystic fibrosis. At present, aggressive antibiotic therapy is the only choice for management of P. aeruginosa infections, but emergence of highly resistant strains necessitated the development of novel alt...

Journal: :iranian biomedical journal 0
اصغر تنومند asghar tanomand صفر فرج نیا safar farajnia شهین نجار shahin najar جعفر مجیدی jafar majidi

background: infections due to pseudomonas aeruginosa are among the leading causes of morbidity and mortality in patients who suffer from impaired immune responses and chronic diseases such as cystic fibrosis. at present, aggressive antibiotic therapy is the only choice for management of p. aeruginosa infections, but emergence of highly resistant strains necessitated the development of novel alt...

Journal: :modares journal of medical sciences: pathobiology 2010
bahareh hajikhani shahin najar peerayeh hourieh soleimanjahi zuhair mohammad hassan

objective: helicobacter pylori is a widely distributed gram negative bacterium that infects the human stomach and duodenum. some antibiotic regimens are subjected to cure the infection but the cost of drugs, poor patient compliance and emerging of antibiotic-resistant strains are limiting the usefulness of these antibiotic therapies. therefore, interest in developing a h. pylori vaccine is grow...

Delavar Shahbaz Zadeh Hamid Mirmohammad Sadeghi Jamshid Faghri, Kamran Pooshang Bagheri, Rahmatolah Yazdani Sharareh Moghim

Objective(s) Staphylococcus aureus is a leading cause of many nosocomial and community acquired infections. According to many reports, antibiotic therapy can not guarantee the eradication of S. aureus infections. Thus designing an adhesin based vaccine could restrain the S. aureus infections. This study designed for construction of a new fusion protein vaccine against S. aureus infections base...

Background: Subunit vaccines are appropriate vaccine candidates for the prevention of some infections. In this study, three immunogenic proteins of Mycobacterium tuberculosis, including HspX, Ppe44, and EsxV as a new construction, were expressed alone and as a fusion protein to develop a new vaccine candidate against tuberculosis infection. Methods: To make the fusion protein, the three genes ...

Objective(s): Infection with Pseudomonas aeruginosa has been a long-standing obstacle for clinical therapy due to the complexity of the genetics and pathogenesis, as well for widespread resistance to antibiotics, thus attaching great importance to explore effective vaccines for prevention and treatment. This paper focuses on the introduction of novel Pseudomonas aeruginosa type IV pili (T4P)-ba...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید