The influence of zinc, iron, cobalt, and manganese on submerged cultures of Fusarium moniliforme NRRL 13616 was assessed by measuring dry weight accumulation, fusarin C biosynthesis, and ammonia assimilation. Shake flask cultures were grown in a nitrogen-limited defined medium supplemented with various combinations of metal ions according to partial-factorial experimental designs. Zinc (26 to 3...

A fusarin C-producing Fusarium moniliforme strain was grown in submerged culture with defined media containing differing amounts of glucose (30 g/l or 90 g/l) and zinc (5 ppb or 3200 ppb). The influence of zinc on fusarin C synthesis and lipid composition was dependent on the initial glucose concentration. In cultures supplied with 30 g/l glucose, zinc inhibited fusarin C and lipid synthesis by...

The Fusarium moniliforme mycotoxins--fusarin C, fumonisin B1, moniliformin and bikaverin--were evaluated for genotoxicity by their ability to induce unscheduled DNA synthesis (UDS) in primary rat hepatocytes. Isolated hepatocytes were exposed to several concentrations of moniliformin (5.0-500 microM), bikaverin (1.0-500 microM), fumonisin B1 (0.5-250 microM), or fusarin C (1.0-100 microM). Afla...

A fusarin C-producing Fusarium monilifomle strain was grown in submerged culture with defined media contaIning differing amounts of glucose (30 gil or 90 g/l) and zinc (5 ppb or 3200 ppb). The influence of zinc on fusarin C synthesis and lipid composition was dependent on the initial glucose concentration. In cultures supplied with 30 gil glucose, zinc inhibited fusarin C and lipid synthesis by...

Background: Identification and quantification of mycotoxins produced by Fusarium species are important in controlling fungal diseases. Objectives: Potential of zearalenone, butenolide and fusarin C production was investigated in five Fusarium graminearum and five F. culmorum isolates at molecular level. Materials and Methods: Presence of PKS13, FG08079.1 and PKS10 genes, associated with produ...

background: identification and quantification of mycotoxins produced by fusarium species are important in controlling fungal diseases. objectives: potential of zearalenone, butenolide and fusarin c production was investigated in five fusarium graminearum and five f. culmorum isolates at molecular level. materials and methods: presence of pks13, fg08079.1 and pks10 genes, associated with product...