introduction: the accuracy of analyzing functional mri (fmri) data is usually decreases in the presence of noise and artifact sources. a common solution in for analyzing fmri data having high noise is to use suitable preprocessing methods with the aim of data denoising. some effects of preprocessing methods on the parametric methods such as general linear model (glm) have previously been evalua...

mri of the breast has evolved as a non-invasive imaging modality and is ideally suited for several indications e.g. pre-operative staging and screening in women at increased risk for breast cancer. the widespread use opens also the discussion on over-diagnosis if only 20 - 30 out of 100 mri - guided breast biopsies lead to the diagnosis of breast cancer. thus mri based strategies are needed to ...

background: chronic daily headache (cdh) has gained little attention in functional neuro-imaging. when no structural abnormality is found in cdh, defining functional correlates between activated brain regions during headache bouts may provide unique insights towards understanding the pathophysiology of this type of headache. methods: we recruited four cdh cases for comprehensive assessments, in...

In the spring of 1991 the first of a group of new methods for mapping human brain function was successfully tested at the MRI Center of the Massachusetts General Hospital, in Boston. These methods use the supremely noninvasive technique of magnetic resonance imaging to create images of the brain that are sensitive to local changes in blood flow. In identification of cortical areas active for a ...