Introduction: One of the most obvious morphological changes due to aging is the formation of facial wrinkles, which are remarkably visible at middle ages and can have a significant effect on the quality of life of individuals. It is believed that UVB is one of the main causes of aging by stimulating reactive oxygen species. Nanoemulsion was loaded with fullerene, a strong free ...

Nanoemulsion is an alternative and promising approach to overcome insolubility and bioavailability problems of bioactive compounds. In this study, the sonication parameter for preparing nanoemulsions with high α- tocopherol and linolenic acid content were optimized by using response surface methodology and their stability were evaluated during 2 months’ storage. The response surface analysis re...

Nanoemulsion is an alternative and promising approach to overcome insolubility and bioavailability problems of bioactive compounds. In this study, the sonication parameter for preparing nanoemulsions with high α- tocopherol and linolenic acid content were optimized by using response surface methodology and their stability were evaluated during 2 months’ storage. The response surface analysis re...

This research aims to formulate and to optimize a nanoemulsion-based formulation containing fullerene, an antioxidant, stabilized by a low amount of mixed surfactants using high shear and the ultrasonic emulsification method for transdermal delivery. Process parameters optimization of fullerene nanoemulsions was done by employing response surface methodology, which involved statistical multivar...

in this study formation and properties of o/w emulsion stabilized by a mixture of sodium caseinate (2, 5 and 10 wt %) and non-ionic emulsifier tween 80, sorbitan mono-9-octadecenoate, (0, 0.5, 1 and 1.5 wt %) were investigated at various ph values(3, 5 and 7) and calcium ion concentrations (0, 0.2, 0.4 and 0.6 wt%). emulsion samples were prepared by using a sonicator with a nominal power output...

Due to the complexity of Alzheimer's disease, multiple cellular types need to be targeted simultaneously in order for a given therapy to demonstrate any major effectiveness. Ultrasound-sensitive coated microbubbles (in a targeted lipid nanoemulsion) are available. Versatile small molecule drug(s) targeting multiple pathways of Alzheimer's disease pathogenesis are known. By incorporating such dr...

Our previous study showed that nanoemulsion-encapsulated MAGE1-HSP70/SEA (MHS) complex protein vaccine elicited MAGE-1 specific immune response and antitumor effects against MAGE-1-expressing tumor and nanoemulsion is a useful vehicle with possible important implications for cancer biotherapy. The purpose of this study was to compare the immune responses induced by nanoemulsion-encapsulated MAG...

Background: Despite the considerable activity of herbal Essential Oils (EOs) as safe food preservatives, problems such as high volatility, low water solubility, and low stability in adverse environmental conditions restrict their use in food products. This work aimed to investigate in vitro antifungal activity of oil-in-water nanoemulsion of Iranian Artemisia dracunculus L. (tarragon) EO. Meth...