adequate intake of folate has an important role in the prevention of nutritional anemia and other complications in childbearing age women. this study was undertaken to determine dietary folate intake and concentration of folate in serum and red blood cell (rbc) in female students of a medical university in tehran, the capital of iran.  in this cross sectional study, 346 female students were ran...

background: coronary artery disease (cad) is emerging as a major public health concern in most developing countries. during the past 10 years, the vast majority of over 100 case-control retrospective studies have shown that elevated plasma homocysteine level is a strong independent risk factor for coronary artery disease. methylenetetrahydrofolate reductase (mthfr) is a key enzyme in folate and...

Research demonstrated that folate deficiency in either the mother or father could impact biological functions of offspring’s neural cells. Folate can also impair methionine cycle, thus contributing to conversion S-adenosylmethionine (SAM) S-adenosylhomocysteine (SAH), which potentially cause damage central nervous system. The study focused on effect parental cell apoptosis offspring neonatal ra...

the aim of this cross sectional study was to determine anemias due to deficiency of iron,vitamin B12 and folate in pregnant women,who were refered to Shahid doctor mofateh hospital in varamin.in this study hemoglobin value(<11g/dl) was used as the determinant of anemia,therefore,the study was performed on 251 pregnant women.the proportions of women having abortions and cesarean sections were 10...

Background: Opium addiction is a global problem which has implicated many societies. Opium addiction and drug abuse is related to harmful consequences which affect life style, biochemical factors, and vitamins values, and also is considered as a risk for heart diseases. Folate and B12 levels are related to homocysteine and studies about their levels in opium addicts are controversial; therefore...

the association between helicobacter pylori (hp) infection and concentration of folate or homocysteine are still unclear. the aim of the present study was to assess the effect of  hp infection on folate and homocysteine concentrations in patients infected with hp and healthy participants. we also assessed dietary intakes of folate, vitamins b6 and b12 in two groups. in this case-control study, ...

Folate plays an important role in metabolism and its deficiency can lead to cardiovascular problems or carcinogenesis. Some studies show that narrow band UVB (NBUVB) causes folate deficiency by photolysis , while others have different opinions or even the contrary. With regard to paradoxes in this context, we decided to study the effect of NBUVB on folate levels in patients with dermatologic di...

Introduction: In recent years, bismuth-based nanomaterials have been widely used in medical researches as imaging, drug delivery and x-ray radiosensitizing agents. Due to their anti-microbial effects against Helicobacter pylori (HP), bismuth colloidal compounds are used to treat various types of diseases such as chronic gastritis. Despite their advantages, bismuth-based compoun...

Research background. Lactic acid bacteria (LAB) are known to produce folate. However, this ability is highly strain-dependent. Folate synthesis in specific LAB strains affected by the availability of folate, which can be consumed other under certain conditions. Moreover, differences folate capabilities related presence biosynthesis-related genes and regulation pathway. Experimental approach. As...