A partially fluorine substituted hydroxyapatite- (FHA-) coated Mg-Zn alloy was prepared to investigate the interfacial behavior of degradable Mg-based biomaterials with degradable bioactive coatings in a cell culture environment. Peaks from the results of X-ray diffraction (XRD) were characterized and compared before and after cell culture. It was found that Ca-P, including poorly crystalline i...

Phthalocyanines and subphthalocyanines are attracting attention as functional dyes that are applicable to organic solar cells, photodynamic therapy, organic electronic devices, and other applications. However, phthalocyanines are generally difficult to handle due to their strong ability to aggregate, so this property must be controlled for further applications of phthalocyanines. On the other h...

Unprecedented divergent rearrangements of cyclopropyl-substituted fluoroepoxides are reported. In the presence of a catalytic amount of benzoic acid, cyclopropyl-substituted fluoroepoxides efficiently undergo 1,5-fluorine migration. However, when the fluoroepoxides are heated with K2CO3 at 60 °C, 1,2-fluorine migration occurs. The 1,5-fluorine migration is believed to proceed via a carbocation ...

Objective(s): The present study aimed to investigate the antibacterial properties of a conventional epoxy-based dental sealer modified with synthesized bioactive glass (BG), hydroxyapatite (HA), and fluorine-substituted hydroxyapatite (FHA) nano-fillers. Materials and Methods: The synthesized nano-fillers were incorporated into the conventional epoxy-based dental seaer at the concentratio...

objective: silicon is an effective element in bone biomineralization; hence si-substituted hydroxyapatite can be a relevant bioceramic as bone materials substitution. materials and methods: stoichiometric hydroxyapatite (ha) and si-substituted hydroxyapatite (si-ha) with different contents of si substitution were synthesized successfully by a hydrothermal method using ca(no3)2, (nh4)3po4 or (n...

A range of crystalline and nano-sized carbonate- and silicate-substituted hydroxyapatite has been successfully produced by using continuous hydrothermal flow synthesis technology. Ion-substituted calcium phosphates are better candidates for bone replacement applications (due to improved bioactivity) as compared to phase-pure hydroxyapatite. Urea was used as a carbonate source for synthesising p...

The replacement of oxygenated functionality (hydroxy and alkoxy) with a fluorine atom is commonly used bioisosteric in medicinal chemistry. In this paper, we use molecular matched-pair analysis to better understand the effects on lipophilicity. It seems that reduced log P compound normally dominant determining size difference. We observe presence additional electron-donating groups an aromatic ...