نتایج جستجو برای: Fim2 و Fim3
تعداد نتایج: 760633 فیلتر نتایج به سال:
Bordetella pertussis fimbriae (Fim2 and Fim3) are components of a five-component acellular pertussis vaccine (diphtheria-tetanus-acellular pertussis vaccine [DTaP5]), and antibody responses to fimbriae have been associated with protection. We analyzed the IgG responses to individual Fim2 and Fim3 in sera remaining from a Swedish placebo-controlled efficacy trial that compared a whole-cell vacci...
زمینه و هدف: فیمبریه(Fim2 و Fim3) از فاکتورهای حدت در Bordetella pertussis است و باعث اتصال باکتری به سلولهای مژه دار دستگاه تنفس میزبان و تحریک پاسخهای ایمنی میشود. فیمبریه از ارکان اصلی واکسنهای سلولی و بدون سلولی سیاه سرفه محسوب میشود. طبق پیشنهاد سازمان بهداشت جهانی (WHO) در واکسنهای سلولی باید حضور فیمبریه (Fim2 و Fim3) تایید شده باشد. در این تحقیق برای برر...
As established by Eldering et al. (3), fimbrial antigens of Bordetella pertussis cells were used to raise agglutinating antibodies and have thus been called agglutinogens, which are constitutive parts of two fimbrial proteins, Fim2 and Fim3, and of an outer membrane protein called pertactin (Prn), respectively (1, 2). On the basis of this, monoclonal antibodies to Fim2 and Fim3 were obtained (4...
We analyzed temporal changes in the frequencies of the ptxA, prn, fim2, and fim3 alleles in Bordetella pertussis strains isolated from pertussis patients in Moscow, Russia, from 1948 to 2004. The three strains used for the whole-cell vaccine harbored the alleles ptxA2, ptxA4, prn1, fim2-1, and fim3A. Vaccine-type alleles of ptxA (ptxA2 and ptxA4) were characteristic for all prevaccination strai...
Denaturation of Bordetella pertussis fimbrial preparations by guanidinium hydrochloride (GdnHCl) has been characterized using static light scattering, c.d., fluorescence and antibody recognition. The susceptibility of Fim2 + 3 (a mixed preparation of two fimbrial types) to GdnHCl was found to be highly dependent on pH; as the pH was increased from pH 7.2 to 10.5, the concentration of GdnHCl req...
OBJECTIVES To investigate changes in virulence-related genotypes and in the antimicrobial susceptibility of Bordetella pertussis isolates collected from the 1970s to 2014 in the northern part of China. METHODS A total of 124 B. pertussis isolates from three periods, the 1970s, 2000-2008, and May 2013-Sept 2014, were typed by multilocus sequence typing (MLST) and tested for antimicrobial susce...
∗ Corresponding author: Pertussis Reference Laboratory, Department of Bacteriology and Microbiology Research Center, Pasteur Institute of Iran. Email: [email protected] ertussis or whooping cough, caused by Bordetella pertussis, is one of the important vaccine preventable diseases. Pertussis vaccination is recommended as a part of routine childhood immunization. The whole cell per...
BACKGROUND As has occurred in many regions worldwide, in 2012 the incidence of pertussis increased in Perú. This epidemiologic situation has been associated with a waning vaccine-induced immunity and the adaptation of Bordetella pertussis to vaccine-induced immunity along with improved diagnostic methods. METHODS The study comprised a total of 840 pertussis-suspected cases reported in Perú du...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید