to evaluate the effects of local administration of the fetal brain extract (fbe) on the crushed peripheral nerve, 15 male wistar rats were used. the right sciatic nerve of 10 rats was locally underwent the tense compression for 30 seconds and then randomly divided into experimental and control (sham) groups. the remained rats were considered as intact animals. treatment was commenced weekly, by...

background access to appropriate images of fetal brain can greatly assist to diagnose of probable abnormalities. the aim of this study was to compare the suitability of t2-true fast imaging with steady state free precession (t2-trufi), and t2-half-fourier acquisition single-shot turbo spin-echo (t2- haste( magnetic resonance imaging (mri) to extract the fetal brain using the level set algorithm...

objective(s): nowadays much effort is being invested in order to diagnose the mechanisms involved in neural differentiation. by clarifying this, making desired neural cells in vitro and applying them into diverse neurological disorders suffered from neural cell malfunctions could be a feasible choice. thus, the present study assessed the capability of fetal brain extract (fbe) to induce rat bon...

Background Access to appropriate images of fetal brain can greatly assist to diagnose of probable abnormalities. The aim of this study was to compare the suitability of T2-True Fast Imaging with Steady State Free Precession (T2-TRUFI), and T2-Half-Fourier Acquisition Single-Shot Turbo Spin-Echo (T2- HASTE( magnetic resonance imaging (MRI) to extract the fetal brain using the level set algorithm...

introduction: it is clear that the proliferation, migration and differentiation processes of embryonic fetal neural tissue are dependent on special trophic factors. these factors are absent or lessl seen in adult tissue. in this research the effects of fetal brain extract (fbe) on the regenerational processes of lesioned prepheral nerve were investigated. materials and methods: the facial nerve...

Fetal MRI is an essential tool for analyzing morphological changes of fetal brain structure. The automated methods developed for adult brain extraction are unsuitable for fetal brain extraction because of the differences in tissue types and tissue properties between adult and fetal brain. However, only few automated fetal brain segmentation methods are available. In this paper we propose a full...

background: methamphetamine (ma) is a potent psychomotor stimulant with high abuse and addictive potential. ma is a neurotoxic drug which is widely abused by females of childbearing age, raising serious public health concerns in terms of exposure of the fetus to the drug. neurotoxic effects of ma on adult are well known, such as dopaminergic nerve terminal degeneration and cell death in regions...

alcohol directly affects astroglial cell function, including inflammation-related activity.  and it also affects microglial cell development and function in specific ways that interfere with microglial interactions with the immune system and with neurons. neuroinflammatory processes might be involved in alcohol-induced brain damage. alcohol use, misuse and getting used to it causes different ki...

introduction: there are several different molecular pathways in tissue damage by ischemic brain injury. the use of antioxidants and free radical scavengers are a matter of attention by some researchers. crocus sativus (saffron) is used previously for protective effects in ischemia state by some researchers. to assess pathologic aspects of neuroprotection of saffron in some susceptible brain are...

neuroinflamation occurring after traumatic brain injury (tbi) is a complex phenomenon comprising distinct cellular and molecular events involving the injured cerebral tissue. mechanical injury to adult rat brain elucidated the accumulation in the affected area of trophic activity. in the tissue adjacent to the injury, trophic titers began to rise after the lesion. this study aimed to determine ...