A small laboratory fermentor which employs mechanical agitation for the dispersion of air introduced under pressure has previously been described by Feustel and Humfeld (1946). This fermentor has an operating capacity of 500 to 2,000 ml and has been found very useful for small-scale, yeast-culturing investigations, as well as for studies on the production of subtilin activity by Bacillus subtil...

The productivity of enzyme fermentations depends critically on maintaining a high oxygen transfer rate to satisfy the optimal oxygen demand of the microorganism for product formation. Among the several factors that affect oxygen transfer rates in a fermentor are the air flow rate and agitation. The production of a-amylase by Bacillus amyloliquefaciens was performed in 600-mL and 5-litre ferment...

McDANIEL, L. E. (Rutgers, The State University, New Brunswick, N.J.), E. G. BAILEY, AND A. ZIMMERL. Effect of oxygen-supply rates on growth of Escherichia coli. II. Comparison of results in shake flasks and 50-liter fermentor. Appl. Microbiol. 13: 115-119. 1965.-Growth of Escherichia coli and chemical changes in the medium were very similar in highly baffled flasks and in a 50-liter fermentor r...

McDANIEL, L. E. (Rutgers, The State University, New Brunswick, N.J.), E. G. BAILEY, AND A. ZIMMERL. Effect of oxygen-supply rates on growth of Escherichia coli. II. Comparison of results in shake flasks and 50-liter fermentor. Appl. Microbiol. 13: 115-119. 1965.-Growth of Escherichia coli and chemical changes in the medium were very similar in highly baffled flasks and in a 50-liter fermentor r...

Polygalacturonase production under different shear stress environments by Aspergillus sp. was studied. It was found that the rate of enzyme production in the stirred tank fermentor decreased with increasing the stirrer speed in the range 300-750 rpm. On the other hand, in a split cylinder air-lift fermentor, the rate of polygalacturonase production slightly increased with increasing in air ...

The scale-up criterion of constant oxygen mass transfer coefficient (kLa) was applied for the production of itaconic acid (IA) in a 50 L pilot-scale fermentor by the fungal cells of Aspergillus terreus. Various operating conditions were examined to collect as many kLa data as possible by adjusting the stirring speed and aeration rate in both 5 L and 50 L fermentor systems. In the fermentations ...

polygalacturonase production under different shear stress environments by aspergillus sp. was studied. it was found that the rate of enzyme production in the stirred tank fermentor decreased with increasing the stirrer speed in the range 300-750 rpm. on the other hand, in a split cylinder air-lift fermentor, the rate of polygalacturonase production slightly increased with increasing in air rate...

Batch and continuous production of the extracellular heme glycoprotein chloroperoxidase (CPO) was studied with an airlift fermentor. We induced Caldariomyces fumago CMI 89362 to form pellets by transferring a small inoculum volume in preculture prior to growth in a 1-liter fermentor. Continuous replacement of the fructose-salts medium (dilution rate, 0.008 h) supported continuous CPO formation ...