Trigonella foenum graecum commonly known as Fenugreek exerts normoglycemic and insulinotropic effects in humans by compounds from its seed and leaf extracts. Some studies reported that treating pregnant mice with fenugreek seed could cause toxic effects on the nervous system of its pubs during developmental growth, while in some other studies neuroprotective properties were considered for it. S...

An experiment was conducted to assess the effect of dietary supplementation of garlic (Allium sativum) and fenugreek (Trigonella foenum-graecum L.) seed powder as herbal feed additives on growth performance, carcass characteristics and economics of feeding in broilers. A total of 320 day old broiler chicks of Cobb-400 strain were divided into four treatment groups with 4 replicates of 20 chicks...

BACKGROUND/OBJECTIVE The purpose of the present study was to evaluate the effect of fenugreek seed extract in combination with swimming exercise compared to glibenclamide consumption on type 2 diabetic rats. DESIGN The acute toxicity test was carried out to choose the safe doses and identify the toxicity effects of the fenugreek seed extract. To investigate the hypoglycemic effect of the extr...

It was found that fenugreek seed extract reduced the body weight gain induced by a high-fat diet in obese mice. The extract decreased plasma triglyceride gain induced by oil administration. The major component of the extract, 4-hydroxyisoleucine, also decreased plasma triglyceride gain. Consequently, fenugreek seed extract is expected to prevent the obesity induced by a high-fat diet.

Fenugreek is a common herb possessing several bioactive components including diosgenin. Here, dietary fenugreek seed flour and diosgenin were evaluated on a model of endothelium-dependent vasorelaxation by abdominal aortas isolated from rats receiving high-fat, high-sugar diet (HFHSD). 60 male Wistar rats were randomized into six groups: (i) negative control getting conventional rat feed regime...

s: Background: Several studies have reported the hypoglycemic property of Fenugreek seeds (Trigonella foenum graecum), a commonly used condiment in Indian homes, due to its high dietary fiber content. Method: A total of 25 NIDDM patients were given control diets orally consisting of (i)milled rice(boiled rice),(ii) whole wheat (chapati) experimental diets consisting of (iii) boiled rice with fe...

BACKGROUND Primary dysmenorrhea is a prevalent disorder and its unfavorable effects deteriorates the quality of life in many people across the world. Based on some evidence on the characteristics of fenugreek as a medical plant with anti-inflammato-ry and analgesic properties, this double-blind, randomized, placebo controlled trial was conducted. The main purpose of the study was to evaluate th...

Many traditional treatments have been recommended in the alterative system of medicine for the diabetes mellitus. Current research is now directed towards finding naturally occurring antidiabetic properties from plant origin. In Indian system of medicine Trigonella foenum graecum is an important medicinal plant and its leaves and seeds have been used in various ailments and as a health tonic. T...

In the present study, investigations were carried out to screen the anticancer activities of fenugreek seed oil against cancer cell lines (HEp-2, MCF-7, WISH cells), and a normal cell line (Vero cells). Cytotoxicity was assessed with MTT and NRU assays, and cellular morphological alterations were studied using phase contrast light microscopy. All cells were exposed toi 10-1000 μg/ml of fenugree...

OBJECTIVE Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia condition resulting from defective insulin secretion or resistance insulin action, or both. The purpose of this study was to evaluate the effect of 6 weeks swimming training and Trigonella foenum-graecum seed (fenugreek) extract, alone and in combination, on plasma glucose and cardiac antioxidant...