conclusions fentanyl and fentanyl plus lidocaine effectively decreased the hemodynamic response to tracheal intubation, however, neither fentanyl nor fentanyl plus lidocaine, could inhibit all hemodynamic responses, moreover fentanyl plus lidocaine was not more effective than fentanyl alone. background induction of anesthesia and endotracheal intubation often creates a period of hemodynamic ins...

Human neonates and infants can become tolerant and dependent during continuous fentanyl or morphine administration. The long-term consequences in these individuals as juveniles and adults are unknown. This study compared fentanyl self-administration behavior in juvenile rats that were opioid naive or were exposed chronically to fentanyl as infants. Postnatal day 14 infant rats remained naive or...

Background: The risk of anesthesia increases with age, so it is necessary to choose a safe and effective method. In this study, we compared the effectiveness of intranasal fentanyl with intravenous fentanyl in patients undergoing cataract surgery. Methods: This study was a triple-blind prospective randomized clinical trial (The patient, physician, and data analyzer were unaware of the patient ...

results the sedative effects were equal in the two groups (p > 0.05), but the analgesic effects were higher in the pf group than in the pk group (p < 0.05). the pk group had higher blood pressure levels in the eighth minute. respiratory rate, heart rate, and arterial oxygen saturation showed no significant differences between the groups (p > 0.05). endoscopist satisfaction, patient satisfaction...

conclusions iv bolus injection of propofol-ketamine can lead to more patients’ satisfaction than the other protocols during colonoscopy. results mean satisfaction scores in the group pk were significantly higher than the group pf (p = 0.005) while the level of sedation during the procedure was similar (p = 0.17). hemodynamic parameters and spo2 values were not significantly different (p > 0.05)...

background various attempts have been made to reduce the incidence of fentanyl-induced cough during anesthesia induction. we hypothesized that an appropriate dose of propofol might suppress fentanyl-induced cough. objectives a study had been designed to observe the effects of propofol on a fentanyl-induced cough during anesthesia induction. patients and methods we performed a randomized, double...

The United States and numerous other countries worldwide are currently experiencing a public health crisis due to the abuse of illicitly manufactured fentanyl (IMF) and its analogues. This manuscript describes the development of a liquid chromatography-tandem mass spectrometry-based method for the multiplex detection of N = 24 IMF analogues and metabolites in whole blood at concentrations as lo...

BACKGROUND Fentanyl, a synthetic opioid, is a popular choice amongst anaesthesiologists in the operating room. Pre induction intravenous fentanyl bolus is associated with coughing in 28-65% of patients. Fentanyl induced cough is not always benign and can be remarkably troublesome at the most critical moment of anaesthesia when airway reflex is lost. OBJECTIVES To study the effect of pre empti...