In some Mediterranean areas-mainly the Balearic Islands, Sardinia, Sicily, Greece, Cyprus, and Israel-where the cultivation and consumption of broad beans (Vicia faba) are extensive, favism is rather common especially in children. It occurs after the inhalation of some, as yet unidentified constituent(s) of the plant and/or more often after eating the beans, especially when they are fresh. The ...

BACKGROUND G6PD deficiency is the most common enzymopathy of red blood cells. The clinical symptoms of favism are jaundice, hematuria and haemolytic anaemia that seem to affect liver and kidney in long term. Thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a high rate of fava beans cultivation. METHODS This study was performed on favism pati...

In Greece, favism is the most common type of acute haemolytic anaemia in childhood (Kattamis, unpublished). The disease seems to be restricted mainly to certain Mediterranean countries (Sardinia, Greece, and Israel, especially among Sephardic Jews); lately, it has also been described in other areas of the world (Motulsky and Stamatoyannopoulos, 1966). Many aspects of the pathogenesis of favism ...

Favism is a severe, acute haemolytic anaemia which occurs in about 20% of G6PD deficient subjects after ingestion of fava beans. Since not all G6PD deficient subjects are sensitive to fava beans, the possibility has been suggested that extra erythrocytic factors may play an important role in the susceptibility to haemolytic favism. To test the hypothesis that an autosomal enzyme is involved in ...

Objectives: to examine the methods used diagnose favism at Al-Rammadi Pediatric Hospital in adult patients who have a history of condition.Patients and method: The investigation was conducted from January 1 December 31, 2021. group then divided into two. Throughout course trial, participants were all admitted pediatric hospital diagnosed with favism. Any protracted met routine medical practice ...

Favism is an acute hemolytic anemia known to occur in susceptible individuals who ingest fava beans. Susceptibility to favism is conferred by a genetic deficiency in erythrocytic glucose-6-phosphate dehydrogenase (G6PD) activity. Although the fava bean pyrimidine aglycones, divicine and isouramil, have been implicated in the onset of favism in humans, the lack of a well-defined experimental ani...