BACKGROUND Although previous studies have helped define the natural history of Duchenne muscular dystrophy (DMD)-associated cardiomyopathy, the myocardial pathobiology associated with functional impairment in DMD is not yet known.The objective of this study was to assess the distribution of transverse relaxation time (T2) in the left ventricle (LV) of DMD patients, and to determine the associat...

By identifying the effect of any parameter such as distance, attenuation and scattering on the Line Spread Function (LSF), one can compensate the quantitative and qualitative destructive effect of such parameters by deconvolution method. Using a 99mTC line source, this study was performed on a single head ADAC SPECT system operating in planar mode. Variation of FWTM and FWHM and LSFs as a...

The size of the Gaussian kernel defines the "width" of the curve which determines in turn how much the data is smoothed. The width is not expressed in terms of the standard deviation ?, as customary in statistics, but with the Full Width at Half Maximum (FWHM). In this case the FWHM would be 2.35: The maximum of this curve is y = 0.4 at x = 0. The half maximum is y = 0.2 at x = -1.175 and at x ...

The size of the Gaussian kernel defines the "width" of the curve which determines in turn how much the data is smoothed. The width is not expressed in terms of the standard deviation ?, as customary in statistics, but with the Full Width at Half Maximum (FWHM). In this case the FWHM would be 2.35: The maximum of this curve is y = 0.4 at x = 0. The half maximum is y = 0.2 at x = -1.175 and at x ...

1 Kapteyn Astronomical Institute Rijks-universiteit Groningen (RuG), Landleven 12, Groningen 9747 Netherlands e-mail: [email protected] 2 Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago, Chile 3 European Southern Observatory, Karl-Schwarzschild-Str.2, D 85748 Garching bei München, Germany 4 Anton Pannekoek Astronomical Institute, University of Amsterdam, PO Box 942...

Using computer simulations and high-resolution fMRI experiments in humans (n=6) and rats (n=8), we investigated to what extent BOLD fMRI temporal resolution is limited by dispersion in the venous vasculature. For this purpose, time-to-peak (TTP) and full-width at half-maximum (FWHM) of the BOLD impulse response (IR) function were determined. In fMRI experiments, a binary m-sequence probe method...

Previous models of cardiac Ca2+ sparks have assumed that Ca2+ currents through the Ca2+ release units (CRUs) were approximately 1-2 pA, producing sparks with peak fluorescence ratio (F/F(0)) of approximately 2.0 and a full-width at half maximum (FWHM) of approximately 1 microm. Here, we present actual Ca2+ sparks with peak F/F(0) of >6 and a FWHM of approximately 2 microm, and a mathematical mo...