known origin (FUO) as persistent fever higher than 38.3°C (101°F) that lasts for 3 weeks with no established diagnosis despite 1 week of inpatient investigations. More recently, the definition of FUO has been updated to reflect developments in medicine and technology; FUO is now defined as persistent fever higher than 101°F for 3 weeks and failure to make a diagnosis with 3 outpatient visits or...

BACKGROUND Fever of unknown origin (FUO) is a diagnostic challenge. Rheumatologists are often in charge of patients with FUO because the vasculitides, especially, are potential and common causes of FUO. OBJECTIVE To evaluate the value of a standardised investigation to identify the cause of FUO. METHODS A standardised work-up programme for patients with FUO was started at the beginning of S...

INTRODUCTION Fever of unknown origin (FUO) is one of the most challenging diagnostic dilemmas in the field of infectious diseases and tropical medicine. Clinicians should use the frequency distribution of disorders causing FUO to guide their diagnostic approach in patients with prolonged, unexplained fevers meeting the definition of FUO. METHODOLOGY The present study was undertaken to examine...

BACKGROUND Although infectious diseases are the most common sources for the fever of unknown origin (FUO), but the spectrum of infectious diseases is changing overtime. The purpose of the study was to define the clinical spectrum and changing the pattern of FUO. METHODS This existing data based study was undertaken from 2007 to 2011. One hundred-six patients fulfilling the modified criteria f...

OBJECTIVES Fever of unknown origin (FUO) remains a challenge in clinical practice. Fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is helpful in diagnosing the etiology of FUO. This paper aims to develop a completely automatic classification method based on PET/CT data for the computer-assisted diagnosis of FUO. METHODS We retrospectively analyze...

Background Fever of unknown origin (FUO) is a challenging problem worldwide. FUO, as defined by Petersdorf and Beeson in 1961 [1] , includes illness persisting for 3 weeks or more, occasional episodes of a fever 38.3°C or more, and an unclear cause upon examination after one week of hospitalization. Recently, only one retrospective study of FUO have been conducted in the south China, but there ...

I n elderly patients, the syndrome of fever of unknown origin (FUO) differs in several important regards from that seen in younger patients. The causes of FUO in the elderly are rarely benign or selflimited; almost always, an elderly patient with FUO will be found to have a serious illness as the cause of the fever.':" Factitious and fraudulent causes of FUO are exceedingly rare in the elderly....

To elucidate the causes of fever of unknown origin (FUO) in Taiwan, we retrospectively analyzed the characteristics of 78 adult patients meeting the classic criteria for fever of unknown origin who were treated at National Taiwan University Hospital from July 1999 through June 2002. Cause of FUO was due to infections in 42.3% of patients, neoplasms in 6.4%, noninfectious inflammatory diseases i...

OBJECTIVE The causes of fever of unknown origin (FUO) vary depending on the region and time period. We herein present a study of patients with classic FUO where we investigated differences based on patient background factors, such as age and causative diseases, and changes that have occurred over time. METHODS We extracted and analyzed data from the medical records of 256 patients ≥18 years o...

The original criteria for fever of unknown origin (FUO) as set forth in 1961 by Petersdorf and Beeson were fever higher than 38.3°C on several occasions of at least 3 weeks’ duration and uncertain diagnosis after 1 week of study in the hospital (1). This definition was later revised, and the criterion of 1 week of hospitalization has been replaced by 3 days of hospitalization or three outpatien...