This paper challenges the assertion made by FLEGG and TOHMO, 2011 that the FLQ non-survey method of estimating regional trade will improve the accuracy of STONE's, 1969 RAS algorithm when applied within the context of constructing regional input-output tables. The paper firstly raises a number of conceptual concerns with the assertion before presenting empirical evidence regarding the efficacy ...

BACKGROUND Around 70-90% of peptic ulcer disease (PUD) is due to Helicobacter pylori and requires treatment with antimicrobials to which these bacteria are susceptible. Common H. pylori diagnostic tests do not provide drug susceptibility data. Using the GenoType HelicoDR PCR test designed for gastric biopsies for simultaneous detection of H. pylori and its resistance to clarithromycin (CLA)/flu...

Background The interaction between different drug-resistant mutations is important to the development of drug resistance and its evolution. In this study, we aimed to reveal the potential relationships between mutations conferring resistance to two important antituberculosis drugs streptomycin (STR) and fluoroquinolones (FLQ). Materials and methods We used an in vitro competitive fitness assa...

The GenoType MTBDRsl test and DNA sequencing were used to rapidly detect second-line drug- and ethambutol (EMB)-resistant Mycobacterium tuberculosis. The ability of these two assays to detect the presence of mutations associated with resistance to fluoroquinolones (FLQ), aminoglycosides/cyclic peptide (AG/CP), and EMB in the gyrA, rrs, and embB genes (for the GenoType MTBDRsl test) and gyrA, gy...

The Cantonese sentences in (2) illustrate these claims. They denote past events and there are no markers attached to the verb (subclaim (1a)). Subclaim (1b) is illustrated by the minimal pair in (2b) and (2c): the latter describes a current situation and the former, with the temporal adverb ML FLQ ‘formerly’, describes a past event. (The superscripts in the Cantonese renderings are tone markers.)

The use of location quotients for the estimation regional input–output tables has been found to be a useful and efficient tool estimate intraregional production coefficients multipliers. This paper considers some regionalisation methodologies based on tables—some which have hitherto not analysed at level—and studies one provides best (best goodness fit). We focus analysis mainly accuracy Flegg’...