نتایج جستجو برای: FEF25-75/FVC

تعداد نتایج: 459  

2014
Bruno Sposato Marco Scalese Maria Giovanna Migliorini Maurizio Di Tomassi Raffaele Scala

PURPOSE Our study tried to find a relationship between baseline FEF25-75% and airway hyperresponsiveness (AHR) and whether a greater FEF25-75% impairment may be a marker of a more severe hyperresponsiveness in subjects with normal FEV1 and FEV1/FVC and suggestive asthma symptoms. Besides, we tried to asses a FEF25-75% cut-off value to identify hyper-reactive subjects. METHODS 4,172 subjects (...

Journal: :Respiration; international review of thoracic diseases 2016
Mario Malerba Alessandro Radaeli Alessia Olivini Giovanni Damiani Beatrice Ragnoli Valentina Sorbello Fabio L M Ricciardolo

BACKGROUND Forced expiratory flow at 25 and 75% of the pulmonary volume (FEF25-75%) might be considered as a marker of early airway obstruction. FEF25-75% impairment might suggest earlier asthma recognition in symptomatic subjects even in the absence of other abnormal spirometry values. OBJECTIVES The study was designed in order to verify whether FEF25-75% impairment in a cohort of subjects w...

Journal: :International journal of health sciences 2016
Mohamed Faisal Lutfi

BACKGROUND The pattern of change in FEF50%, FEF25%-75% and FEF50%/FEF25%-75% ratio depends on mechanics of forceful expiration, provided that non-homogenous lung emptying is faithfully recorded in the expiratory flow-volume loops. OBJECTIVE To assess the potential clinical value of FEF50%, FEF25%-75% and FEF50%/FEF25%-75% ratio as an indicator of bronchial asthma (BA) control. METHODOLOGY T...

2004
D L DeMeo V J Carey H A Chapman J J Reilly L C Ginns F E Speizer S T Weiss E K Silverman

Background: The Boston Early-Onset COPD study showed that current or ex-smoking first degree relatives of severe early onset COPD probands have significantly lower forced expiratory volume in 1 second (FEV1) and FEV1/forced vital capacity (FVC) values than current or ex-smoking control subjects, which suggests the existence of genetic risk factors for the development of COPD in response to ciga...

Journal: :PloS one 2015
Craig M Riley Sally E Wenzel Mario Castro Serpil C Erzurum Kian Fan Chung Anne M Fitzpatrick Benjamin Gaston Elliot Israel Wendy C Moore Eugene R Bleecker William J Calhoun Nizar N Jarjour William W Busse Stephen P Peters W Gerald Teague Ronald Sorkness Fernando Holguin

INTRODUCTION FEF25-75 is one of the standard results provided in spirometry reports; however, in adult asthmatics there is limited information on how this physiological measure relates to clinical or biological outcomes independently of the FEV1 or the FEV1/FVC ratio. PURPOSE To determine the association between Hankinson's percent-predicted FEF25-75 (FEF25-75%) levels with changes in healthc...

2009
Seung Hun Jang Hye Ryun Kang Dong Gyu Kim

Background: The methacholine bronchial provocation test is a useful tool for evaluating asthma in patients with normal or near normal baseline lung function. However, the sensitivity of this test is 82∼92% at most. The purpose of this study is to evaluate the clinical usefulness of FEF25-75% in identification of airway hyperresponsiveness in patients with suspected asthmatic symptoms. Methods: ...

Journal: :Journal of biological regulators and homeostatic agents 2012
G Ciprandi M A Tosca I Cirillo E Lionetti S Leonardi M Miraglia Del Giudice M La Rosa A Salpietro M Capasso G L Marseglia

Allergic rhinitis and asthma are closely associated. Inflammation is a common pathological characteristic shared by both disorders. The measure of the fractional concentration of exhaled nitric oxide (FeNO) may be considered a surrogate marker for airway inflammation. Forced expiratory flow between 25 and 75 percent of vital capacity (FEF25-75) has been previously demonstrated to be able to pre...

2017
Ayşegül Karadeniz Mevlüt Karataş

Introduction: We investigated whether expiratory high resolution computed tomography (EHRCT) is superior to the pulmonary function test (PFT) in showing small airway disease (SAD) in patients with isolated mitral valve stenosis (MVS). Methods: Sixty patients contributed to the study prospectively. Cases were divided into three groups (mild, moderate, severe) on the basis of MVS and PAP. Results...

Journal: :American journal of respiratory and critical care medicine 2003
Frank D Gilliland Kiros Berhane Yu-Fen Li Edward B Rappaport John M Peters

Both in utero exposures to maternal smoking and asthma are associated with chronic deficits in lung function. We hypothesized that in utero exposure affects lung function in children without asthma and synergistically affects children with early onset asthma. To investigate effects of in utero exposure and age at asthma diagnosis on lung function, we examined longitudinal medical history, tobac...

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