the aim of this study is to prepare novel sorbitol based extended release tablets by melt dispersion method using carbamazepine as a model drug. carbamazepine was melted along with sugar alcohol to get melt dispersion granules (mgds) and was characterized by differential scanning calorimetry (dsc), powder x-ray diffractometry (xrd) and solubility study. the physical and chemical parameters of m...

The goal of this study was to design and evaluate extended - release system of the hypnotic agent, Zolpidemtartrate usefulness for the treatment of insomnia. The half-life of this drug is about 1.9 - 3 hours that indicatingit a candidate for the extended release formulation. Our investigation relates to development of extendeddrug delivery system based on Hydroxy propyl methyl cellulose (HPMCK4...

Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...

1 INDICATIONS AND USAGE Alfuzosin hydrochloride extended release tablets are indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. 1.1 Important Limitations of Use Alfuzosin hydrochloride extended release tablets are not indicated for the treatment of hypertension. Alfuzosin hydrochloride extended release tablets are not indicated for use in the pediatric population...

extended-release matrix tablets of diltiazem hydrochloride (dtz) were prepared using waxy materials alone or in combination with kollidon sr. matrix waxy materials were carnauba wax (cw), bees wax (bw), cetyl alcohol (ca) and glyceryl monostearate (gms). dissolution studies were carried out by using a six stations usp xxii type 1 apparatus. the in vitro drug release study was done in 1000 ml ph...

Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...

Abstract The main aim of this study was to prepare and evaluate the extended - release system of an anxiolytic substance. Alprazolam is a short-acting benzodiazepine with general properties similar to those of diazepam. Our studies focused on the development of extended drug delivery system based on Hydroxy Propyl Methyl Cellulose (HPMC 4000cps) as retard agent and polyvinylpyrrolidone (PVP k30...

Nifedipine Extended-release Tablet depends for its action on the existence of an osmotic gradient between the contents of the tablet core and fluid in the gastrointestinal tract. Drug delivery is essentially constant as long as the osmotic gradient remains constant, and then gradually falls to zero. Upon swallowing, the biologically inert components of the tablet remain intact during gastrointe...

Metformin helps your body to better use the insulin your pancreas. . Many people find the Extended Release version is more tolerable. Pharmacokinetics and pharmacodynamics of extended-release glipizide GITS compared with immediate-release glipizide in patients with type II diabetes . 2 Answers (question resolved) Posted in: glipizide xl, glipizide, pharmacy, generic Answer: ER or XL means exten...

the purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. matrix system was the earliest oral extended release platform for medicinal use. matrix tablets are most commonly used methods to modulate the release profile of drugs. they are much desirable and preferred for such therapy because they offer be...