introduction: estrogen and progesterone are supposed to modify pain sensitivity. however, the actual role of each of these steroid hormones in this respect is not well known. plasma concentrations of these hormones show variation during estrous cycle. the role of alpha2 receptors in tonic pain has been pointed out. the aim of the present study was to investigate the agonist and antagonist effec...

background: estradiol and progesterone as well as hippocampal gabaa receptors are believed to play a role in the modulation of pain. the aim of present study was to investigate the effect of intrahippocampal injections of gabaa receptor agonist (muscimol) and gabaa receptor antagonist (picrotoxin) on pain sensitivity during estrous cycle. methods: pain sensitivity was evaluated in rats by forma...

melanocortin- 4 receptor (mc4r) and agouti- related peptide (agrp) are involved in energy homeostasis in rats. according to mc4r and agrp effects on luteinizing hormone (lh) secretion, they may influence the estrous cycle of rats. therefore, the aim of this study was to investigate the expression of mc4r and agrp mrnas at different stages of estrous cycle in the rat’s hypothalamus. the estrous ...

objective: considering the importance of integrin molecules in the implantation and lack of sufficient information in the expression pattern of these molecules in various phases of estrous cycle. it seemed to be necessary to investigate these molecules in mouse endometrial during the various phases of oestrous cycle. materials and methods: female nmri mice (n=15) aged 6-8 weeks were studied. v...

This study was designed to investigate the relationship between the estrous cycle phases with uterine bacterial and fungal flora in non-pregnant female rabbits. Thirty laboratory mature multiparous rabbits were used for this purpose. Samples from uterine lavage for culture of bacteria and fungi were collected at different stages of estrous cycle (based on vaginal cytology), and histopathologica...

introduction: in female rats sensitivity to antinociceptive treatment varies during estrous cycle stages. the role of gaba through gabab receptor in nociception has been established. the aim of the present study is to investigate the effect of intercerebroventicular injection of gabab receptor agonist (baclofen) and gabab antagonist (cgp35348) on pain sensitivity during different stages of estr...

to investigate the igg content and its variations in uterine fluid (uf) during the estrous cycle of the cow and to compare them with those of the blood serum (s), six pairs of serum and uf samples for each phase of the cycle selected out of 240 bovine genital tracts and blood samples were collected from urmia abattoir. the uf samples were collected by gentle scraping of the endometrium using a ...

Melanocortin- 4 receptor (MC4R) and agouti- related peptide (AgRP) are involved in energy homeostasis in rats. According to MC4R and AgRP effects on luteinizing hormone (LH) secretion, they may influence the estrous cycle of rats. Therefore, the aim of this study was to investigate the expression of MC4R and AgRP mRNAs at different stages of estrous cycle in the rat’s hypothalamus. The estrous ...

Introduction: In female rats sensitivity to antinociceptive treatment varies during estrous cycle stages. The role of GABA through GABAB receptor in nociception has been established. The aim of the present study is to investigate the effect of intercerebroventicular injection of GABAB receptor agonist (baclofen) and GABAB antagonist (CGP35348) on pain sensitivity during different stages of estr...