BACKGROUND We determined the optimal inspired sevoflurane concentration for use during labour as 0.8% in our previous study. This study compared sevoflurane at a concentration of 0.8% and Entonox((R)) (nitrous oxide 50%: oxygen 50%) for analgesia during labour in 32 healthy parturients. METHODS Each mother underwent two open-label, three-part sequences in random order, Entonox-sevoflurane-Ent...

BACKGROUND AND OBJECTIVE: Entonox is an odorless, tasteless gas and the first anesthesia agent used in obstetrics. To date, no studies have evaluated the effects of Entonox on oxidative stress. This study aimed to investigate the association between infant oxidative stress indices in mothers exposed to Entonox gas during vaginal delivery. METHODS: This cohort study was conducted on 120 pregnant...

The arterial oxygen saturation of 40 mothers in the first stage of labour was monitored using pulse oximetry. Half the mothers received epidural analgesia and the rest inhaled Entonox for pain relief. Eight mothers in the Entonox group and six in the epidural group had at least one episode of significant hypoxia (saturation < 90%). There was little difference in the number of hypoxic episodes e...

BACKGROUND Although there are various methods for painless delivery such as using entonox gas, most of the people are unfamiliar or concerned about it yet. OBJECTIVES The purpose of this study was to assess maternal expectations and experience of labor analgesia with nitrous oxide. PATIENTS AND METHODS In a clinical trial study, 98 pregnant women in active phase of delivery were studied ran...

BACKGROUND/AIMS Panretinal photocoagulation (PRP) reduces the risk of visual loss in proliferative diabetic retinopathy but some patients cannot tolerate PRP because of pain. Inhaled Entonox was evaluated as an analgesic during PRP. METHODS A randomised, crossover, double masked pilot study was performed. Patients inhaled either air or Entonox and half the PRP was applied. The treatment was c...

Background Renal colic is a painful medical emergency, needs urgent intervention to reduce pain. Nonsteroidal anti-inflammatory drugs, opioids, and entonox are pain-relieving agents. This study was aimed to compare fentanyl + entonox (nitrous oxide + O2) versus fentanyl + oxygen. Materials and Methods One hundred and twenty patients with acute renal colic presenting to the emergency departmen...

Background and aim Entonox was one of the important methods for pain management in the delivery process. In previous years some studies have assessed the effect of this method in Iran. In this regard, the aim of this study was to systematically review studies addressing the effect of Entonox for pain management in labor. Methods This systematic review and meta-analysis study was conducted in ...

We intend to begin offering Entonox (a medical anaesthetic gas comprising 50% nitrous oxide and 50% oxygen) as an analgesic choice for women attending for intrauterine device (IUD) fittings or difficult removals in our community contraception clinics. Entonox is already used for short-term pain relief in the community by district nurses and midwives, and in the hospital emergency and obstetric ...

BackgroundSince the relief of pain in patients with acute myocardial infarction (AMI) is very important; we sought to assess the effect of Entonox as an analgesic drug in our subjects. Our goal was to compare the analgesic effect of Entonox with opioid drugs such as morphine and meperidine. MethodsThis study was a randomized clinical trial, which included 120 patients with wellestablished AMI a...

AIM To compare colonoscopy quality with nitrous oxide gas (Entonox®) against intravenous conscious sedation using midazolam plus opioid. METHODS A retrospective analysis was performed on a prospectively held database of 18608 colonoscopies carried out in Lothian health board hospitals between July 2013 and January 2016. The quality of colonoscopies performed with Entonox was compared to intra...