background rheumatoid arthritis (ra) is the most common chronic inflammatory disease. the staphylococcal superantigens are considered as the causative agent of ra disease. objectives this study aimed to assess the presence of staphylococcal enterotoxin d in synovial fluid and blood of patients with ra. patients and methods a total of 120 blood and sf samples of patients with ra were studied. ba...

background: staphylococcus aureus, the major virulence factor of hospital and community acquired infections, secretes numerous exotoxins (super antigens), which may affect immunological and inflammatory status in psoriatic skin lesion. objectives: this study is designed to compare the s. aureus super antigens level in sera of psoriatic patients with normal cases (nevus). patients and methods: a...

Cholera-like enterotoxin produced by a non-O1 strain of Vibrio cholerae, S7 (S7 enterotoxin), isolated from human diarrheal stool, was purified, and its physicochemical, biological, and immunological properties were compared with those of cholera enterotoxin from V. cholerae O1 569B (CT) and an enterotoxin produced by another non-O1 V. cholerae (E8498 enterotoxin) reported previously (Yamamoto ...

Objective: The study is focused on evaluating the efficacy of seaweed flavonoids against staphylococcus enterotoxin A. Methods: drug-likeness and pharmacological properties chosen ligand were evaluated using SWISS ADME. AutoDockTools-1.5.6 was used to carry out docking analysis determine binding parameters with molecular modeling. Docking visualization performed discovery studio. Results: bioac...

The epidemiological and bacteriological investigations on four foodborne outbreaks caused by a new type of enterotoxin-producing Clostridium perfringens are described. C. perfringens isolated from patients of these outbreaks did not produce any known enterotoxin and did not carry the C. perfringens enterotoxin gene. However, the culture filtrates of these isolates induced the accumulation of fl...

Identification of a new enterotoxin was accomplished by purification of the enterotoxin produced by staphylococcal strain FRI-326 and by preparation of specific antitoxin to the enterotoxin. Toxicity of the preparations was determined in rhesus monkeys, and specificity of the enterotoxin-antitoxin reaction was determined in gel diffusion plates. The enterotoxin was designated enterotoxin E.

Staphylococcal enterotoxin types A and C, were observed by viscosimetry and near-ultraviolet difference spectroscopy to unfold at concentrations of aqueous guanidine hydrochloride greater than 1 M. Apparent rate constants of unfolding calculated from spectral curves differed markedly for the two enterotoxins. Rate constants for the unfolding of enterotoxin A in 2 or 3 M guanidine hydrochloride ...

Sixty-nine strains of Clostridium perfringens of different toxigenic types were investigated for enterotoxin production. Enterotoxin was definitively detected only in strains of types A and C. This is the first report where enterotoxin production has been demonstrated in a toxigenic type other than type A. The exterotoxin-positive type C strains were isolated from cases of enteritis necroticans...