enamel matrix derivative emdogain (emd) is widely used in periodontal treatment in spite of the fact that its effect on the developing embryo has not been elucidated. the aim of this study was to investigate the teratogenic effect of emd on the rat embryo neural crest cells. the neural crest is a unique population of cells that migrates from the dorsal neural tube along defined pathways and pro...

objective: the aim of this study was to compare subepithelial connective tissue grafts (sctg) and coronally advanced flaps (caf) with the addition of emdogain in the treatment of gingival recession. materials and methods : this interventional randomized controlled clinical trial involved eleven patients and 31 teeth demonstrating facial recessions of > 2 mm identified as miller's class i or ii....

background: the aim of this clinical trial study was to clinically evaluate the use of enamel matrix protein derivative combined with the coronally positioned fl ap to treat gingival recession compared to the subepithelial connective tissue graft by a new method to obtain denuded root surface area. materials and methods: thirteen patients, each with two or more similar bilateral miller class i ...

Enamel matrix derivative is used to promote periodontal regeneration during the corrective phase of the treatment of periodontal defects. Our main goal was to analyze the bioactivity of different molecular weight fractions of enamel matrix derivative. Enamel matrix derivative, a complex mixture of proteins, was separated into 13 fractions using size-exclusion chromatography and characterized by...

The purpose of bone tissue engineering is to employ scaffolds, cells, and growth factors to facilitate healing of bone defects. The aim of this study was to assess the viability and osteogenic differentiation of primary human osteoblasts and adipose tissue-derived mesenchymal stem cells from various donors on titanium dioxide (TiO2) scaffolds coated with an alginate hydrogel enriched with ename...

Following a review of periodontal wound healing, this article discusses techniques designed to optimise including guided-tissue regeneration and using enamel matrix derivatives. Enamel derivatives are porcine derived, thought stimulate differentiation, proliferation, migration mineralization in cells found tissues. This charts the development surgical outcomes from regenerative techniques, addi...