نتایج جستجو برای: Efflux pump genes
تعداد نتایج: 501296 فیلتر نتایج به سال:
conclusions adeabc efflux system plays a vital role in multidrug resistance in clinical a. baumannii isolates. it was noted that the most important gene responsible for multidrug resistance within this system was the adeb gene especially in carbapenems resistance. methods this study was conducted on 84 multidrug resistant and 13 carbapenem-susceptible a. baumannii isolates obtained from burn an...
Introduction: In the past decade, multidrug-resistant Acinetobacter baumannii has become one of the most critical challenges in treating infected patients. The AdeABC efflux pump is the most important among the various resistance mechanisms. This pump can force various antibiotics and ethidium bromide out of the bacterial cell to the surrounding environment. Methods: In this study, nine A. baum...
conclusions the efflux pump may play a role in antibiotic resistance in a. baumannii isolates. the ability of a. baumannii isolates to acquire drug resistance by the efflux pump mechanism is a concern. thus, new strategies are required in order to eliminate the efflux transport activity from resistant a. baumannii isolates causing nosocomial infections. background acinetobacter baumannii has em...
background: this study aimed to evaluate the role of efflux pump regulator and oxa-23 genes in imipenem resistance acinetobacter baumannii strains isolated from hospitalized patients in tehran, iran. methods: this study was conducted on 60 a. baumannii isolates collected from patients admitted to the shahid motahari and taleghani hospitals in tehran during 2013-14. antibiotic susceptibility tes...
background and objectives: pseudomonas aeruginosa (pa) is one of the most important causes of nosocomial infections and has an intrinsic resistance to many antibiotics. among all the resistance-nodulation-division (rnd) pumps of p. aeruginosa, mexab-oprm is the first efflux pump found to target multiple classes of antibiotics. this study was aimed to evaluate the expression level of genes expre...
Background and purpose: Acinetobacter spp. is a non-fermentative gram- negative bacterium involving in various nosocomial infections. During last decade increasing number of multidrug-resistant isolates of Acinetobacter spp. have been reported. This type of resistance is possibly related to efflux pumps. This research aimed at identifying the phonotypic and genotypic characteristics of efflux p...
Background: This study aimed to evaluate the role of efflux pump regulator and OXA-23 genes in imipenem resistance Acinetobacter baumannii strains isolated from hospitalized patients in Tehran, Iran. Methods: This study was conducted on 60 A. baumannii isolates collected from pa...
Background: The increasing emergence of antimicrobial resistance among gram negative bacteria especially Enterobacteriaceae has become a global problem. Klebsiella pneumoniae is an opportunistic pathogen, which recently due to causing broad spectrum of disease and antibiotic resistance has been lionized. Efflux pumps are one of the antibiotic resistance mechanisms, which were introduced in t...
Introduction: Acinetobacter baumannii is an important bacteria because of high ability to obtain antibiotic resistance genes and creation of multi-drug resistant strains (MDR). Today, the active efflux pumps has been suggested as one of the most important mechanisms of intrinsic and acquired resistance of antibiotics in bacteria. The aim of this study was Evaluation of phenotypic and genotypic ...
Introduction: One of the important factors causing nosocomial infections is drug-resistant Staphylococcus aureus strain, so correspondingly, having norA efflux pump is one of the bacterial's ability to generate drug resistance. Iron has been used as a nanoparticle with antimicrobial activity against bacteria. The aim of this study was to investigate the effect of iron oxide nanoparticles synthe...
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