The anxiolytic effect of the flower of Echium. amoenum was shown in several experimental studies in mice. The present study was aimed to determine whether tolerance develops to anxiolytic action of E. amoenum in mice. NMRI male mice were injected intraperitoneal with hydroalcoholic extract (12.5, 25 and 50 mg/kg) or saline once each day (8 am) for period of 7 days and then tested on light/dark ...

OBJECTIVE Echium amoenum Fisch. & C.A. Mey. is used for the treatment of various diseases in traditional medicine. This plant is a major source of anthocyanins with beneficial cardiovascular properties such as anti-atherosclerotic and antihypertensive effects. In the present study, the protective and antioxidant effects of anthocyanin-rich E. amoenum extract were evaluated on human vascular end...

Echium amoenum belong to Boraginaceae family is a biennial or perennial herb indigenous to the narrow zone of northern part of Iran and Caucasus.the aim of this study was to overview the therapeutic effects of Iranian borage (Echium amoenum Fisch).This review article was carried out by searching studies in PubMed, Medline, Web of Science, and Iran Medex databases .The initial search strategy id...

A new semi-theoretical thin-layer model of the fluidized bed drying of Echium amoenum Fisch. & C.A. Mey. petals has been developed. Experiments were conducted under different conditions: temperatures of 40, 50 and 60 °C, and air velocities of 0.5, 0.75 and 1.0 m/s, until the moisture content decreased to 0.04.-0.06 kg of water per kg of dry matter. Drying processes in the fluidized bed were com...

Background & Aims: Echium amoenum and Citrus aurantifolia are used in traditional medicine for the treatment of cardiac arrhythmia and regulation of blood pressure. In this study the effects of coadministration of these herbs on heart rate and blood pressure of rats before and after phynelephrine injection were investigated. Methods: Ten groups of rats respectively received 100, 200, 400 an...

INTRODUCTION Borage (Echium amoenum) is a large annual plant of the Boraginaceae family that grows in most parts of Europe and in northern parts of Iran. The flower of borage is used as a medicinal herb in various countries as an antifebrile and antidepressant, for treatment of stress, circulatory heart diseases and pulmonary complaints, as a poultice for inflammatory swellings, as a diuretic, ...

Medicinal plants are recognized as sources of natural antioxidants that can protect from biological system oxidative stress. The present cross-sectional before/after clinical trial was carried out to investigate the antioxidant properties of the decoction of the flowers of Echium amoenum Fisch & C.A. Mey in humans. A group of 38 healthy subjects was invited to use the E. amoenum (7 mg kg(-1)) t...