the knee bracing steel frame (kbf) is a new type of energy dissipating frame which enjoys exceptional ductility and lateral stiffness. rather than the beam-column joint, one end of the diagonal brace in kbf is attached to the knee element. indeed, the knee element as a hysteretic damper is designed and detailed to behave like a structural fuse by sustaining controlled inelastic deformations as ...

The knee bracing steel frame (KBF) is a new type of energy dissipating frame which enjoys exceptional ductility and lateral stiffness. Rather than the beam-column joint, one end of the diagonal brace in KBF is attached to the knee element. Indeed, the knee element as a hysteretic damper is designed and detailed to behave like a structural fuse by sustaining controlled inelastic deformations as ...

from the time that civil engineers have used steel in building structures, they tried to increase its strength so as to produce more economic and lighter structures by using more elegant sections. increase of steel strength is not always useful for all members of a steel structure. in some members under certain conditions, it is needed to reduce the strength as much as possible to improve the b...

A proper composition of stiffness and ductility parameters is required to obtain a resistant and economic structure. Accordingly, Chevron Knee Braced Frame (CKBF) seems appropriate due to its proper seismic performance. The advantage of this system comes to having the capability of rapid and cheap replacement of chevron knee elements after an earthquake occurs. In this research, response modifi...

BACKGROUND A method for inhibiting the expression of particular genes using external guide sequences (EGSs) has been developed in bacteria, mammalian cells and maize cells. RESULTS To examine whether EGS technology can be used to down-regulate gene expression in Caenorhabditis elegans (C. elegans), we generated EGS-Ngfp-lacZ and EGS-Mtgfp that are targeted against Ngfp-lacZ and Mtgfp mRNA, re...

Ribonuclease P complexed with external guide sequence (EGS) bound to mRNA represents a unique nucleic acid-based gene interference approach for modulation of gene expression. Compared with other strategies, such as RNA interference, the EGS-based technology is unique because a custom-designed EGS molecule can hybridize with any mRNA and recruit intracellular ribonuclease P for specific degradat...

The pathogenesis of equine grass sickness (EGS) has not fully understood. A better understanding of the exact pathogenesis of diseases can help to make an accurate diagnosis. Previous studies reported some pathological damage of neuronal cells in EGS patients. In this study, primarily cytotoxicity of serum from three clinically EGS-diagnosed horses on PC12 Tet-off (PTO) cells was assessed. Subs...

RNase P complexed with external guide sequence (EGS) represents a novel nucleic-acid-based gene interference approach to modulate gene expression. In this study, a functional EGS RNA was constructed to target the overlapping mRNA region of two human cytomegalovirus (HCMV) capsid proteins, the capsid scaffolding protein (CSP) and assemblin. The EGS RNA was shown to be able to direct human RNase ...