For many years electromagnetic fields (EMFs) have been used clinically with various settings as an exogenous stimulation method to promote fracture healing. However, underlying mechanisms of action and EMF parameters responsible for certain effects remain unclear. Our aim was to investigate the influence of defined EMFs on human osteoblasts' and osteoclasts' viability and function. Primary huma...

Objective(s): It is known that extremely low frequency-pulsed electromagnetic fields (ELF-PEMF) influence multiple cellular and molecular processes. Retinal pigment epithelial (RPE) cells have a significant part in the emergence and pathophysiology of several ocular disorders, such as neovascularization. This study assessed the impact of ELF-PEMF on the proangiogenic features of RPE cells. Mate...

Current interest in the application of pulsed electromagnetic field (PEMF) as alternative therapy for different medical conditions has proved to be successful. A number of investigations demonstrated that low frequency PEMF enables the induction of significant current in tissues and allows for an enhanced biological effect and thus, can facilitate wound healing. In our previous study [1] we pre...

Background: This study investigated the effects of extremely low frequency (ELF) pulsed electromagnetic field (PEMF) radiation on the growth of bacterium Staphylococcus aureus (ATCC 25923) that plays a versatile role in infecting wounded tissues. The viability of these bacteria (number of live cells as colony-forming units (CFUs)) was measured before and after the ELF PEMF exposures to quantify...

For this investigation, we studied the effects of extremely low frequency pulse electromagnetic fields (ELF-PEMF) on the human cardiac signal. Electrocardiograms (ECGs) of 22 healthy volunteers before and after a short duration of ELF-PEMF exposure were recorded. The experiment was conducted under single-blind conditions. The root mean square (RMS) value of the recorded data was considered as c...

Fracture-healing is a highly complex and timely orchestrated process. Non-healing fractures are still major clinical problem treatment remains difficult. A 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) was identified as non-invasive adjunct therapy supporting bone-healing by inducing reactive oxygen species (ROS) Ca2+-influx. However, ROS Ca2+-influx may stimulate neutro...

This paper presents the experimental pilot study to investigate the effects of pulsed electromagnetic field (PEMF) at extremely low frequency (ELF) in response to photoplethysmographic (PPG), electrocardiographic (ECG), electroencephalographic (EEG) activity. The assessment of wavelet transform (WT) as a feature extraction method was used in representing the electrophysiological signals. Consid...

Extremely low frequency electromagnetic fields (ELF-EMFs) are non-ionizing, low-energy, fields, capable of inducing biological effects such as cell migration, proliferation and differentiation, cytokine growth factors expression, NO signaling alteration. In vitro experiments have shown an interaction ELF-EMFs with all the phases wound healing. This in knowledge could be applied clinical practic...

The purpose of this study was to evaluate whether 50 Hz extremely low frequency electromagnetic fields (ELF-EMFs) affect the amount of orthodontic tooth movement in rats. The experiments were performed on 18 male Sprague-Dawley rats. The rats were randomly divided into three groups (n = 6): cage-control (Cg-Cnt) group (n = 6); sinusoidal electromagnetic field (SEMF) group (n = 6); and pulsed el...

the efficacious effects of pulsed electromagnetic field (pemf) under the certain field parameters like frequency and the field intensity have been reported for various tissue and molecules. since collagen is found abundantly in most tissue structures, this research was designed to further investigate the effects of extremely low frequency (elf) pemf on the synthesis of the epidermal collagen. t...