BACKGROUND/AIMS H. pylori CagL amino acid polymorphisms such as Y58/E59 can increase integrin α5β1 expression and gastric cancer risk. Hypochlorhydria during chronic H. pylori infection promotes gastric carcinogenesis. The study test whether CagL-Y58/E59 isolates may regulate integrin α5β1 to translocate CagA via the type IV secretory system even under adverse pH conditions, and whether the int...

The type IV secretion system (T4SS) is a major virulence determinant of the gastric pathogen Helicobacter pylori. The CagL protein is a specialized adhesin of the corresponding T4SS pilus, which establishes initial contact with the integrin β1 receptor on host target cells. Recent studies proposed that Y58 and E59 amino acid polymorphisms in CagL increase the virulence of H. pylori strains by e...

Enterovirus 71 (EV71) and coxsackievirus (CVA) are the most common causative factors for hand, foot, and mouth disease (HFMD) and neurological disorders in children. Lack of a reliable animal model is an issue in investigating EV71-induced disease manifestation in humans, and the current clinical therapies are symptomatic. We generated a novel EV71-infectious model with hSCARB2-transgenic mice ...

A stumbling point for many learning to fly fish is being able to fly cast well enough to ‘present’ a fly to a feeding fish. Even among more skilled fly fishers, learning to fly cast better is often a bottleneck towards advancement in the sport. Fly casting instruction today relies on the visual inspection of the fly casting stroke and the resulting ‘loop’ of fly line. These qualitative visual c...

abstract background and purpose : stroke is a leading cause of death and functional disability. while there have been major advances regarding the management of stroke, a significant proportion of people are still unaware of stroke-related symptoms and risk factors. this study was performed to assess the public awareness and attitude of stroke warning signs and risk factors among a sample of ir...

Free AccessImportant Keywordshttps://doi.org/10.14220/9783737013444.259SectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInRedditEmail About Previous chapter Next FiguresReferencesRelatedDetails Download book coverOsnabrücker Studien zur Jüdischen und Christlichen Bibel.Volume 8 1st editionISBN: 978-3-8471-1344-7 eISBN: 978-3-7370-1344-4Hi...

â â â â  kangwon national university, south korea â â yonsei university, south korea â â  [1] â  kangwon national university, south korea â â â  abstract â  t his paper aims to understand the structure and determinants of international bank l ending among apec economies. specifically, this paper first aims to analyze whether australia canada japan chinese taipei and the united states, which are...