conclusions this study showed that mmt did not markedly alter the concentration of serum adiponectin in drug abusers. however, in regard to the variations in the serum lipid profiles and anthropometric parameters, the findings indicated that low concentrations of serum adiponectin might play a role in the pathogenesis of obesity and other metabolic abnormalities. thus, more long-term studies wi...

background there is a high risk of tuberculosis (tb) infection among injecting drug users (idus). objectives this study aimed to determine the frequency of latent and active tb infection among idus. materials and methods in a cross-sectional study between 2008 and 2009, idus referred to the methadone maintenance treatment (mmt) centers in hamedan-iran, undergone tuberculin skin test (ppd; purif...

conclusions there is a need to train health staff, and the community, concerning preventive measures, treatment, and reducing harm for substance drug users. results among 402 idus patients, a large amount of them were male, single, and younger than 39 years. regarding psychotic and somatic symptoms caused by methadone therapy, most of the participants had no problem with methadone maintenance t...

conclusions this study demonstrated the detection of hcv-specific ifn-γ responses in hcv antibody and rna negative individuals, with a tendency for hcv-specific ifn-γ responses to be associated with hcv exposure. the potential role of hcv-specific ifn-γ responses in those who remained hcv rna negative is of value for the development of novel hcv therapeutics. objectives in a cohort of hcv antib...

results mean age of the participants was about 35 years, and mean duration of marriage was 14 years. drug dependence of the husband (p = 0.010) and lower monthly income of the family (p = 0.007) predicted the higher level of anxiety among the participants, while older age (p = 0.031), shorter marital duration (p = 0.016), and lower educational level (p = 0.045) in addition to spousal drug depen...

conclusions this study demonstrated improved analgesic effects after using intravenous patient controlled analgesia with ketamine on postoperative pain in opium abusers. patients and methods after institutional review board approval for ethical considerations, a randomized double-blinded placebo controlled clinical trial was conducted. a total of 140 male patients aged 18-65 years, undergoing o...

background to get more precise responses when gathering information about sensitive topics such as drug use, it is important to use the most optimal method. objectives this study was carried out to address the impact of three interview methods (street-based, household, and telephone interviews) on response pattern to sensitive and non-sensitive questions in terms of participation, disclosure an...

results: most addict patients had a medium level of education. improvement in knowledge, attitude and practice (kap) of patients after intervention was observed as follows; decreasing kap in poor level (2.8% vs. 30.6%), (3% vs. 50%), (25% vs. 80.6%), respectively; also, increasing kap in fair level (7% vs. 55.6 %), (15% vs. 15%), (19% vs. 7%), respectively and increasing kap in satisfactory lev...

conclusions: it can be concluded that cognitive-behavioral and spiritual training was effective for the improvement of mental health of hiv positive drug addicts. results: the result of the present research showed that cognitive-behavioral trainings with an emphasis on spirituality were effective for improving quality of life, regarding general aspects of mental and physical health, sub-scales ...