tuberculosis is an infectious disease caused by mycobacterium tuberculosis and is the primary cause of mortality in the world. m. tuberculosis strains are important intracellular pathogens causing infection in oxygen-rich macrophages in the lungs. the emergence of aids, declined socioeconomic standards and a lessened emphasis on tb control programs have contributed to the disease resurgence. re...

descriptive case report of a 42-year old woman with coetaneous vasculitis, and severe abdominal pain, which was led to diagnostic laparotomy. these presentations are probably as a side effect of methocarbamol injection. this is the first report according to our literature search (pubmed, google scholar, isi web of knowledge, proquest, md consult, science direct, scopus) about methocarbamol rela...

purpose: to describe the clinical signs, diagnosis and treatment of toxic keratopathy in a patient who abused tetracaine drops. case report: a 32-year-old man was referred to the emergency ward of our center with persistent corneal epithelial defect associated with a ring infiltrate in the corneal stroma, without any history of ocular trauma or contact lens use. the patient was hospitalized and...

prohibitins are chaperone proteins highly conserved among eukaryotes. many different functions have been attributed to prohibitins depending on their tissue expression and sub-cellular localization. prohibitins play a major role in mitochondrial physiology, regulating the stability and the processing of both respiratory chain complex subunits and opa1, a mitochondrial fusion regulating protein....

background and aims : adverse drug reactions (adrs) are one of the major leading causes of death in the world. this study was designed and conducted because of the importance of adverse events in the cancer treatment setting and regarding this issue there is no study exploring adverse reactions of acute hematologic malignancy chemotherapy in iranian population. methods : this was a prospective,...

background increases in aminotransferases (transaminitis) are potential major adverse reactions seen with long-term use of methotrexate (mtx). the aim of this study, therefore was to evaluate the incidence of mtx induced hepatotoxicity and its risk factors among rheumatoid arthritis (ra) patients. methods this retrospective study described 286 patients with ra who received ≤ 7.5 mg mtx weekly...

objective:the purpose of this study was to investigate the effects of piroxicam co-administration with ethanolic stem-bark extract of khaya senegalensis on biomarkers of oxidative stress and gastro-toxicity in wistar rats. materials and methods: thirty healthy male and female albino wistar rats (190-220 g) were grouped into six (n = 5) with designated treatments including: normal saline, piroxi...

background:every day, people with addiction cause heavy economic and cultural damage to society. in some circumstances, opioids are used as a tool for suicide, which is often seen in youth. the aim of this study was to investigate the clinical signs of toxicity associated with opium in patients referred to ardabil city hospital. methods:this is a cross-sectional study that has been done on opiu...

abstract   background: lead toxicity is caused by ingestion, inhalation, or contact with particles or vapors containing lead. it can present with nonspecific signs and symptoms such as abdominal pain, constipation, irritability, difficulty concentrating, and anemia. in this study, we have tried to find a relationship between lead poisoning and drug abuse.   methods: in a cross sectional study, ...