BACKGROUND Poor compounding practices by the New England Compounding Center resulted in the 2012-2013 fungal infections outbreak. Contaminated injectable methylprednisolone led to the diagnosis of fungal infections in 751 patients and 64 deaths. In the United States, pharmacy compounding has traditionally been regulated by state boards of pharmacy rather than the FDA. To minimize safety risks r...

OBJECTIVES To provide background information related to the development of the Nuclear Pharmacy Compounding Guidelines, to discuss regulatory complexities related to radiopharmaceutical compounding practice, and to summarize the gaps in the current compounding regulations for radiopharmaceuticals. DATA SOURCES The Guidelines closely follow the provisions of section 503A of the Federal Food, D...

Many college students have difficulties in understanding and making connections among the main concepts of statistics. Compounding the difficulties is the misconception of a variety of statistical concepts that students hold even before taking any statistics course. It is, thus, crucial to investigate how the understanding of statistical concepts is constructed and at which stage students start...

Pharmacists are the only health care providers formally trained in the art and science of compounding medications. Therefore pharmacists are expected, by the medical community and the public, to possess the knowledge and skills necessary to compound extemporaneous preparations. Pharmacists have a responsibility to provide compounding services for patients with unique drug product needs. This Te...

n engl j med 367;21 nejm.org november 22, 2012 1969 requiring drugs to be safe and properly labeled. In 1962, a requirement was introduced for proof of drug efficacy through “adequate and well-controlled investigations,” partly in response to the thalidomide tragedy. Rules protecting humanresearch subjects owe a debt to Tuskegee and Nuremberg. Sometimes it takes a disaster to spur the adoption ...

Because of the current inavailability of Kinevac, the form of sincalide for injection approved by the U.S. Food and Drug Administration (FDA), nuclear medicine clinics may consider alternatives, including purchasing a compounded product, and some pharmacists may be considering compounding this drug (1). However, several concerns relative to compounded sincalide make such practices ill advised. ...

Nilavarai Curnam, a compound drug formulation in Siddha System of Medicine was analysed. The Microscopic methods of identifying their ingredients, Chemical analysis, Fluorescence, and Thin Layer Chromatographic studies of the drug have been reported here.

In this article the factors likely to cause spoilage of the drugs of the Indian systems of medicine are reviewed. Methods for the prevention of spoilage are discussed. The results of a limited study carried out on the stability of a few selected drug preparations representing the main dosage forms are also presented.

Brahmyadiyoga a compound drug was used on fourteen Chronic Unmada patients suffering from 2 years to 8 years between the ago range of 18 to 40 years of either sex. The dose of the drug was 8 gms. to 16 gms. for three months. Assessments were done independently by Ayurvedic physician, Psychiatrist and Clinical Psychologist. Seven out of 10 patients who underwent treatment for three months and al...