A simple and fast FI colorimetric procedure for determination of doxorubicin hydrochloride (DXH) was proposed. It is based on the redox reaction between iron (III) and DXH, resulting in an intensely red colored complex in the presence of 1, 10-orthophenantroline which can be followed by spectrophotometric measurement at λmax= 510 nm. This is an automatic way to determine doxorubicin hydrochlori...

objective(s): nowadays hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. temperature and ph-responsive delivery systems have drawn much attention because some diseases reveal themselves by a change in temperature and/or ph. the objective of this work is to prepare and characterize composite membrane using responsive nanoparticles into a polymer...

Fig. 1. Time course for a patient with refractory Burkitt’s leukemia who suffered from fungemia due to Trichosporon dermatis after chemotherapy. Abbreviations: R-hyper CVAD, rituximab+cyclophosphamide hydrate+vincristine sulfate+doxorubicin hydrochloride+dexamethasone; MTX, methotrexate; R-IVAC, rituximab+ifosfamide+etoposide+cytarabine; R-CODOX-M, rituximab+cyclophosphamide hydrate+vincristine...

In this study, GO@Fe3O4 functionalized with ZnO and modified via chitosan (CS) was used a simple procedure to eliminate doxorubicin hydrochloride (DXH) from aqueous solutions. To that end, cry...

Objective(s): Nowadays hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. Temperature and pH-responsive delivery systems have drawn much attention because some diseases reveal themselves by a change in temperature and/or pH. The objective of this work is to prepare and characterize composite membrane using responsive nanoparticles into a polymer...

Here, we report animal experimental data associated with the article entitled "AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo" (Jung et al., 2017) [1]. We tested the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin hydrochloride in a nude mo...

BACKGROUND Subacute cutaneous lupus erythematosus (SCLE), characterized by nonscarring, photodistributed, annular or papulosquamous plaques, is occasionally induced by medication. It has been strongly associated with antihypertensive medications and terbinafine hydrochloride. OBSERVATION We describe 3 women with breast cancer who developed SCLE-like eruptions after being administered doxorubi...

Objective: This study aimed to observe the therapeutic effect of wet compress of magnesium sulfate combined with vitamin B12 on doxorubicin hydrochloride-induced phlebitis in rabbits. Methods: Doxorubicin hydrochloride (0.2%, each side with 5 ml) was injected within 6 min through bilateral auricular veins to build phlebitic models in 48 rabbits. Forty eight hours later, the 48 rabbits were rand...

Abstract: This study aimed to evaluate DOX∙HCl loaded P(DLLA-CO:60:40) nanoformulations with a copolymer of F127 as potential drug delivery system for cancer. DOX ∙ HCl was encapsulated in Poly DL-lactic acid co castor oil 60:40, P(DLLACO: 60:40) polymer the copolymer/stabilizer Pluronic® F127. The mean diameter cylindrical rod shape nanoformulation particles 248±2.4-260±3.2 nm an acceptable po...

To determine the role of the hepatic sinusoidal endothelium in the hepatic disposition of liposomal doxorubicin, we compared the hepatic pharmacokinetics of doxorubicin hydrochloride and the pegylated, liposomal formulation of doxorubicin (Caelyx). The multiple indicator-dilution technique and electron microscopy were used to study the disposition of doxorubicin and liposomal doxorubicin in the...