background: the purpose of this project was to derive the brachytherapy dosimetric functions described by american association of physicists in medicine (aapm) tg-43 u1 based on high dose rate 192i sources. materials and methods: the method utilized included both simulation of the designed polymethyl methacrylate (pmma) phantom using the monte carlo of mcnp4c and benchmarking of the simulation ...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...

In this study, a 4D dosimetry concept was developed. This concept included a method for calculation of 3D reference absorbed dose matrices at every control point of the delivery using a clinical treatment planning system (TPS). Further, the gamma evaluation method was extended to incorporate the 4 dimension of the TPS calculated dose distributions. The applications of the 4D dosimetry concept o...

The post-implantation dosimetry for brachytherapy using Monte Carlo calculation by EGS5 code combined with the source strength regression was investigated with respect to its validity. In this method, the source strength for the EGS5 calculation was adjusted with the regression, so that the calculation would reproduce the dose monitored with the glass rod dosimeters (GRDs) on a water phantom. T...

An urgent requirement for 3D dosimetry has been recognized because of high failure rate (~25%) in RPC credentialing, which relies on point and 2D dose measurements. Comprehensive 3D dosimetry is likely to resolve more errors and improve IMRT quality assurance. This work presents an investigation of the feasibility of PRESAGE/optical-CT 3D dosimetry in the Radiologic Physics Center (RPC) IMRT H&...

A Strategic Research project was performed at NPL with the aim of investigating issues and potential improvements for light-ion dosimetry. The objectives of the project were: a literature survey, testing a number of dosimeters in the proton therapy beam of Clatterbridge Centre of Oncology (CCO), measurement of dose distributions, measurement and calculation of detector perturbations, explore th...

Dosimetry is the process of calculating the effective radioactive dose that is applied to tumors and organs respectively as a patient undergoes a peptide receptor radionuclide therapy. This work presents the novel application software ‘DoSE8’ that was developed from our group and that incorporates all necessary image processing steps (registration and segmentation) and data handling for (partly...

This study compares the EPID dosimetry algorithms of two commercial systems for pretreatment QA, and analyzes dosimetric measurements made with each system alongside the results obtained with a standard diode array. 126 IMRT fields are examined with both EPID dosimetry systems (EPIDose by Sun Nuclear Corporation, Melbourne FL, and Portal Dosimetry by Varian Medical Systems, Palo Alto CA) and th...

We have constructed a computer controlled translational couch to administer total body irradiation reproducibly and safely. The system has replaced the previous stationary anterior-posterior technique in our institution and 30 plus patients have been treated with it so far. In this technique, patients comfortably lie on a couch in supine and prone positions and are transported slowly through a ...