the pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (iv) and intramuscular (im) administration at a dose rate of 10 mg/kg body weight. ceftazidime concentrations in plasma and urine were determined by microbiological assay. ceftazidime disposition was best fitted by a two-compartmental and a one-compar...

high-dose extended-interval dosage (hded) regimen of aminoglycosides is now considered as the standard dosage strategy in sepsis. although safety and efficacy of this dosing regimen is well studied, but new experiments show increased the risk of resistance development associated with %t>mic less than 60% of the dosing interval following extended interval dosing. moreover, limited information is...

The pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (IV) and intramuscular (IM) administration at a dose rate of 10 mg/kg body weight. Ceftazidime concentrations in plasma and urine were determined by microbiological assay. Ceftazidime disposition was best fitted by a two-compartmental and a one-compar...

Abstract Background The role of 2-[ 18 F]fluoro-2-deoxy-D-glucose ([ F]FDG) positron emission tomography/computed tomography (PET/CT) in children is still expanding. Dedicated paediatric dosage regimens are needed to keep the radiation dose as low reasonably achievable and reduce risk radiation-induced carcinogenesis. aim this study investigate relation between patient-dependent parameters [ F]...

Considering that the dosage of manipulating Moxa plays an important role in obtaining good effects for heat-sensitive moxibustion, it would be valuable to know whether the use of fixed dosage is as effective as the use of an individual one. The paper carried out a rigorous multi-centre randomized controlled trial, and its result demonstrated that the effectiveness of individual eliminate-sensit...

Two dosage regimens of L-asparaginase were investigated to determine differences in the production of abnormal reactions and remission induction. Patients were randomly assigned to receive 200 i.u./kg daily for 14 days (Regimen A) or 1000 i.u./kg twice weekly for 2 weeks (Regimen B). All were in relapse and refractory to several chemotherapeutic agents. Medianduration of diseasewas 11 months in...