Objectives: Anti ischemic reperfusion effect of crude methanol extract of Desmodium gangeticum root had been reported earlier but how is modulating its cardiotonic effect to render cardio-protection is largely unknown. Methods: The inotropic effect of methanol extract of Desmodium gangeticum root was investigated on isolated frog heart and further analyzed the physiological and biochemical effe...

The present study investigate the protective effect of aqueous root extract of Desmodium gangeticum in preserving mitochondrial and sarcoplasmic ATPase during ischemia reperfusion injury. The isolated rat hearts in both drug and control group were subjected to warm ischemia (37°), followed by reperfusion with the Langendorff perfusion system. The aqueous root extract of Desmodium gangeticum (L)...

BACKGROUND This study aims to evaluate the antioxidant potential of the ethyl acetate extract of Desmodium gangeticum root for cardioprotection from ischemia reperfusion-induced oxidative stress. METHODS The in vitro antioxidant potential of the extract was in terms of hydroxyl radical scavenging activity, lipid peroxide scavenging activity, nitric oxide scavenging activity and diphenylpicryl...

Antibacterial properties of hexane, chloroform and aqueous extracts of roots of Acorus calamus, Aristolochia indica, Cyperus rotundus, Desmodium gangeticum, Holostemma ada- kodien and Kaempferia galanga, used in the traditional medicine were studied on Bacillus pumilis and Eschericia coli by disc diffusion method.

Dementia is a mental disorder characterized by loss of intellectual ability sufficiently severe enough to interfere with one's occupational or social activities. Desmodium gangeticum commonly known as Salparni, is widely used in ayurveda for the treatment of neurological disorders. The present work was designed to assess the potential of aqueous extract of D. gangeticum (DG) as a nootropic agen...

dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including alzheimer’s disease. desmodium gangeticum dc. (leguminosae) is widely used in ayurveda for treating various neurological disorders. in the present study, the effectiveness of aqueous extract of d. gangeticum in attenuating scopolamine-induced amnesia in mice was inves...

The antidiabetic effect of various extracts of Desmodium gangeticum (D. gangeticum) was evaluated on normal and streptozotocin (STZ)-nicotinamide induced type-2 diabetic animals. Type-2 diabetes was induced in Wistar albino rats of either sex by the administration of STZ-nicotinamide (40, 110 mg/kg b.w., respectively) intraperitoneally. D. gangeticum (100 mg/kg b.w.) extracts in different solve...

Total alcoholic extract of Desmodium gangeticum, which exhibited significant anti-inflammatory activity, was evaluated for the possible mode of action by studying its antioxidant potential in adjuvant-induced arthritic rats. Activity guided fractionation and isolation were carried out. The phenolics fraction showed maximum potency. Solid phase extraction followed by preparative HPLC of the acti...