نتایج جستجو برای: Decolonization

تعداد نتایج: 1130  

Journal: :Clinical microbiology reviews 2016
Edward J Septimus Marin L Schweizer

Colonization with health care-associated pathogens such as Staphylococcus aureus, enterococci, Gram-negative organisms, and Clostridium difficile is associated with increased risk of infection. Decolonization is an evidence-based intervention that can be used to prevent health care-associated infections (HAIs). This review evaluates agents used for nasal topical decolonization, topical (e.g., s...

2012
Tatiana V Gurieva Martin CJ Bootsma Marc JM Bonten

BACKGROUND Control of methicillin-resistant Staphylococcus aureus (MRSA) transmission has been unsuccessful in many hospitals. Recommended control measures include isolation of colonized patients, rather than decolonization of carriage among patients and/or health care workers. Yet, the potential effects of such measures are poorly understood. METHODS We use a stochastic simulation model in w...

Journal: :Infection control and hospital epidemiology 2014
Susan S Huang Edward Septimus Taliser R Avery Grace M Lee Jason Hickok Robert A Weinstein Julia Moody Mary K Hayden Jonathan B Perlin Richard Platt G Thomas Ray

OBJECTIVE To estimate and compare the impact on healthcare costs of 3 alternative strategies for reducing bloodstream infections in the intensive care unit (ICU): methicillin-resistant Staphylococcus aureus (MRSA) nares screening and isolation, targeted decolonization (ie, screening, isolation, and decolonization of MRSA carriers or infections), and universal decolonization (ie, no screening an...

Journal: :Infection control and hospital epidemiology 2008
M Buehlmann R Frei L Fenner M Dangel U Fluckiger A F Widmer

OBJECTIVE To evaluate the efficacy of a standardized regimen for decolonization of methicillin-resistant Staphylococcus aureus (MRSA) carriers and to identify factors influencing decolonization treatment failure. DESIGN Prospective cohort study from January 2002 to April 2007, with a mean follow-up period of 36 months. SETTING University hospital with 750 beds and 27,000 admissions/year. ...

Journal: :The New England journal of medicine 2013
Susan S Huang Edward Septimus Ken Kleinman Julia Moody Jason Hickok Taliser R Avery Julie Lankiewicz Adrijana Gombosev Leah Terpstra Fallon Hartford Mary K Hayden John A Jernigan Robert A Weinstein Victoria J Fraser Katherine Haffenreffer Eric Cui Rebecca E Kaganov Karen Lolans Jonathan B Perlin Richard Platt

BACKGROUND Both targeted decolonization and universal decolonization of patients in intensive care units (ICUs) are candidate strategies to prevent health care-associated infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). METHODS We conducted a pragmatic, cluster-randomized trial. Hospitals were randomly assigned to one of three strategies, with all a...

2014
E. Carlos Rodriguez-Merchan

Staphylococcus aureus (S. aureus) is the most common organism responsible for orthopaedic surgical site infections (SSIs) after elective joint arthroplasty. Patients who are carriers for methicillin resistant S. aureus (MRSA) have a higher likelihood of having invasive MRSA infections[1]. Some reports have suggested that screening and decolonization of all patients having elective joint arthrop...

Journal: :Clinical orthopaedics and related research 2013
Antonia F Chen Charles B Wessel Nalini Rao

BACKGROUND Staphylococcus aureus is the most common organism responsible for orthopaedic surgical site infections (SSIs). Patients who are carriers for methicillin-sensitive S. aureus or methicillin-resistant S. aureus (MRSA) have a higher likelihood of having invasive S. aureus infections. Although some have advocated screening for S. aureus and decolonizing it is unclear whether these efforts...

Journal: :Infection 2013
P Kohler A Bregenzer-Witteck G Rettenmund S Otterbech M Schlegel

PURPOSE Methicillin-resistant Staphylococcus aureus (MRSA) decolonization is a widely established, though controversial part of many MRSA controlling strategies. The aim of this study was to evaluate our decolonization success rate, identify the risk factors for decolonization failure and determine the optimal duration of follow-up in our low MRSA prevalence setting (2.6 % of isolates). METHO...

Journal: :Current opinion in infectious diseases 2014
Kalisvar Marimuthu Stephan Harbarth

PURPOSE OF REVIEW To describe the latest evidence for methicillin-resistant Staphylococcus aureus (MRSA) infection control strategies, with particular emphasis on active surveillance cultures with contact precautions and targeted decolonization, and their impact. RECENT FINDINGS Several major trials published last year questioned the effectiveness of universal screening and contact precaution...

Journal: :The American journal of managed care 2010
Bruce Y Lee Ann E Wiringa Rachel R Bailey Vishal Goyal G Jonathan Lewis Becky Y K Tsui Kenneth J Smith Robert R Muder

OBJECTIVE To estimate the economic value of preoperative methicillin-resistant Staphylococcus aureus (MRSA) screening and decolonization for cardiac surgery patients. STUDY DESIGN Monte Carlo decision-analytic computer simulation model. METHODS We developed a computer simulation model representing the decision of whether to perform preoperative MRSA screening and decolonizing those patients...

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