background: here we describe a new case of partial distal 10q trisomy in a 6-year-old iranian girl from healthy parents with mental, growth, and psychomotor retardations. methods: additional clinical features include dysmorphic craniofacial features, microcephaly, bilateral hydronephrosis without heart problems, small and rotated low-set ears, bow-shaped mouth, abnormal teeth, short neck, and a...

Multi-objective De Novo linear programming (MODNLP) is problem for designing optimal system by reshaping the feasible set (Fiala [3] ). This paper deals with MODNLP having possibilistic objective functions coefficients. The problem is considered by inserting possibilistic data in the objective functions coefficients. The solution of the problem is defined and established under the using of effi...

The De-Novo programming problem proposed by Zeleny is well-known for its value on designing an optimal system by extending existed resources instead of finding the optimum in a given system with fixed resources. Since few papers are dedicated to explore the De-Novo programming problem with multiple stages and its resolution approach, the De-Novo programming problem is innovatively extended to a...

in farming activities, various resources and inputs are utilized to produce agricultural products.. one of the most important goals of agricultural managers and programmers is to assess the optimal resource allocation for designing an appropriate cultivation pattern. mathematical programming is a common approach to achieve the optimal pattern. in this study, the two approaches of fuzzy de-novo ...

given the importance of transcriptome analysis in various biological studies and considering thevast amount of whole transcriptome sequencing data, it seems necessary to develop analgorithm to assemble transcriptome data. in this study we propose an algorithm fortranscriptome assembly in the absence of a reference genome. first, the contiguous sequencesare generated using de bruijn graph with d...

primary de novo intraosseous carcinoma is a rare neoplastic lesion which commonly occurs in the jaws. it is an epithelial odontogenic malignancy arising from odontogenic epithelial residues in the bone rather than from a preexisting epithelial lesion. in the present case report, the clinical, radiological and histological features of primary de novo intraosseous carcinoma are discussed and its ...

Finding repetitive subsequences in genome is a challengeable problem in bioinformatics research area. A lot of approaches have been proposed to solve the problem, which could be divided to library base and de novo methods. The library base methods use predetermined repetitive genome’s subsequences, where library-less methods attempt to discover repetitive subsequences by analytical approach...

Tandem mass spectrometry is a powerful tool for studying proteins. However, an open problem for proteomics research is how to accurately identify proteins from the experimental mass spectra. De novo sequencing based protein identification is the only feasible approach for finding new proteins and studying protein post-translational modifications. In this paper, we describe our novel hybrid de n...

Small supernumerary marker chromosomes (sSMCs), or markers, are abnormal chromosomal fragments that can be hereditary or de novo. Despite the importance of sSMCs diagnosis, de novo sSMCs are rarely detected during the prenatal diagnosis process. Usually, prenatally diagnosed de novo sSMCs cannot be correlated with a particular phenotype without knowing their chromosomal origin and content; ther...

finding repetitive subsequences in genome is a challengeable problem in bioinformatics research area. a lot of approaches have been proposed to solve the problem, which could be divided to library base and de novo methods. the library base methods use predetermined repetitive genome’s subsequences, where library-less methods attempt to discover repetitive subsequences by analytical approaches. ...