The basic concept of a tracer-kinetic experiment dates back to the 1920's [1]: an indicator is injected rapidly in the blood stream and its concentration in the tissue of interest (mmol/ml tissue) is measured as a function of time. The precise shape and form of these curves depends on the manner in which the agent is injected, and on the properties of the tissue under consideration. If the inje...

Introduction Perfusion is the term applied to capillary blood flow in tissue. Since the blood carries oxygen and nutrition to the tissue through the capillaries, perfusion is important in maintaining tissue viability. The study of brain perfusion has clinical applications due to the changes in perfusion associated with several neurological diseases. Diagnosis, lesion characterisation and follow...

a novel discrete singular convolution (dsc)  formulation  is  presented for the seepage analysis in irregular geometric porous media. the dsc is a new promising numerical approach which has been recently applied to solve several engineering problems. for a medium with regular geometry, realizing of the dsc for the seepage analysis is straight forward. but dsc implementation for a medium with ir...

This paper investigates the pollution effect, and explores the feasibility of a local spectral method, the discrete singular convolution (DSC) algorithm for solving the Helmholtz equation with high wavenumbers. Fourier analysis is employed to study the dispersive error of the DSC algorithm. Our analysis of dispersive errors indicates that the DSC algorithm yields a dispersion vanishing scheme. ...

A novel discrete singular convolution (DSC)  formulation  is  presented for the seepage analysis in irregular geometric porous media. The DSC is a new promising numerical approach which has been recently applied to solve several engineering problems. For a medium with regular geometry, realizing of the DSC for the seepage analysis is straight forward. But DSC implementation for a medium with ir...

This communication introduces a novel scheme for the treatment of free edge supports in the analysis of beams by using the discrete singular convolution (DSC) algorithm. Accommodating free edges has been a challenging issue in the DSC analysis of beams, plates, and shells. An iteratively matched boundary (IMB) method is proposed to overcome the difficulty. Numerical experiments are carried out ...