for a long time, scientists have tried to describe disorders just by genetic or environmental factors. however, the role of epigenetics in human diseases has been considered from a half of century ago. in the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

asthma is a complex, heterogeneous and chronic airway inflammatory disease with different clinical phenotypes caused by diverse triggers and pathophysiological mechanisms. asthma heritability has been established in many genetic studies but it is evident that only genetic elements are not responsible for the development of asthma. increasing rate of asthma incidence during past decades has impl...

in this study, we explained a nanobiosensor for dna sequence detection, featuring sequence specificity, cost efficiency, speed, and ease of use. without the need for labels or indicators, it may be ideal for the detection of biological agents. this review describes recent advances in electrochemical impedance spectroscopy (eis) with an emphasis on using nanoparticles and nanotechnology. a power...

Based on the similarity of prokaryotic DNA to that of mitochondrial DNA, a rapid and efficient method for DNA purification from mitochondrial extracts obtained from different sources, was carried out based on the modification method described by Marmur (1983) which resulted in a high degree of purity (A260/A280=2). In addition we have applied the same technique for the first time to purify...

based on the similarity of prokaryotic dna to that of mitochondrial dna, a rapid and efficient method for dna purification from mitochondrial extracts obtained from different sources, was carried out based on the modification method described by marmur (1983) which resulted in a high degree of purity (a260/a280=2). in addition we have applied the same technique for the first time to purify the ...

There is a discrepancy in telomere length as measured by signal intensity of telomere restriction fragments on gels and fluorescence in situ hybridization analysis. This difference has been ascribed to the X-region, a segment of subtelomeric DNA that is resistant to being cut by restriction enzymes. To explore the nature of this region, we analyzed the digestibility of an artificial seeded telo...

A flexible strategy for the preparation of nanostructures of gold nanoparticles (AuNPs) through DNA directed assembly has been proposed. This strategy would greatly enhance the stability, precision and flexibility in the construction of DNA-base structural and functional devices, and promote the development of DNA nanotechnology.